B-cells play a key role in cancer suppression, particularly when aggregated in tertiary
lymphoid structures (TLS). Here, we investigate the role of B-cells and TLS in endometrial …

Background L1-cell adhesion molecule (L1CAM) was previously reported to carry a poor
prognosis in Stage I, low-risk endometrial cancer (EC). We evaluated the role of L1CAM …

Background Despite the excellent prognosis of Fédération Internationale de Gynécologie et
d'Obstétrique (FIGO) stage I, type I endometrial cancers, a substantial number of patients …

Studies in early-stage, predominantly low-and intermediate-risk endometrial cancer have
demonstrated that L1 cell adhesion molecule (L1CAM) overexpression identifies patients at …

Background: Identification of aggressive endometrioid endometrial carcinomas (EECs) and
non-endometrioid carcinomas (NEECs) is essential to improve outcome. L1 cell adhesion …

Endometrial carcinomas (ECs) are classified into type 1 (less aggressive) and type 2
(aggressive) tumours that differ in genetic alterations. So far, reliable immunohistochemical …

Background L1 cell adhesion molecule (L1CAM) expression has been implicated as risk
factor for disease recurrence in endometrial cancer (EC), most likely due to its role in …

Introduction Intraepithelial CD8+ tumour-infiltrating T-lymphocytes (TIL) are associated with
a prolonged survival in endometrial cancer (EC). By contrast, stromal infiltration of CD8+ TIL …

OBJECTIVE: Presence of tumor-infiltrating lymphocytes (TIL) is of prognostic importance in a
variety of malignancies. This study aims to determine the prognostic value of CD8+ cytotoxic …

Abstract Background The newly developed Proactive Molecular Risk Classifier for
Endometrial Cancer (ProMisE) has consistently been shown to be prognostically significant …