Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known.
The critical role of DA in addiction is supported by converging evidence that has been …

For several decades, addiction has come to be viewed as a disorder of the dopamine
neurotransmitter system; however, this view has not led to new treatments. In this Opinion …

Dopamine (DA) is the most abundant catecholamine in the brain. The involvement and
importance of DA as a neurotransmitter in the regulation of different physiological functions …

Repeated drug use can change dopamine (DA) function in ways that promote the
development and persistence of addiction, but in what direction? By one view, drug use …

Dopamine (DA) plays a major role in motor and cognitive functions as well as in reward
processing by regulating glutamatergic inputs. In particular in the striatum the release of DA …

Dopamine (DA) is a key neurotransmitter modulating essential functions of the central
nervous system (CNS), like voluntary movement, reward, several cognitive functions and …

The involvement of dopamine in drug reinforcement is well recognized but its role in drug
addiction is much less clear. Imaging studies have shown that the reinforcing effects of drugs …

There is general consensus among preclinical researchers that dopamine plays an
important role in the development and persistence of addiction. However, the precise role of …

Advances in neuroscience identified addiction as a chronic brain disease with strong
genetic, neurodevelopmental, and sociocultural components. We here discuss the circuit …

A number of dramatic breakthroughs in the neurobiology of addiction have occurred in the
past 40 years. Two domains will be highlighted: the neurocircuitry of addiction and the …