Abstract Phosphoglycerate kinase 1 (PGK1) is an essential enzyme that catalyzes
adenosine 5′-triphosphate (ATP) production in aerobic glycolysis. In addition to regulating …

Abstract Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the
glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which …

Abstract Phosphoglycerate kinase 1 (PGK1) is an essential enzyme in the aerobic glycolysis
pathway. PGK1 catalyzes the reversible transfer of a phosphate group from 1, 3 …

Cells that undergo normal differentiation mainly rely on mitochondrial oxidative
phosphorylation to provide energy, but most tumour cells rely on aerobic glycolysis. This …

Abstract Phosphoglycerate kinase 1 (PGK1) is the first enzyme in glycolysis to generate a
molecule of ATP in the conversion of 1, 3-bisphosphoglycerate (1, 3-BPG) to 3 …

Cancer cells are able to survive in difficult conditions, reprogramming their metabolism
according to their requirements. Under hypoxic conditions they shift from oxidative …

During the proliferation and metastasis, the tumor cells prefer glycolysis (Warburg effect), but
its exact mechanism remains largely unknown. In this study, we demonstrated that …

Phosphoglycerate kinase 1 (PGK1) is an important enzyme in the metabolic glycolysis
pathway. In this study, we observed a significant overexpression of PGK1 in liver cancer …

Abstract Background/Aims: Tumor dissemination is frequent in gastric cancer and implies a
poor prognosis. Cure is only achievable provided an accurate staging is performed at …

Abstract Phosphoglycerate kinase 1 (PGK1) acts as both a glycolytic enzyme and a protein
kinase playing critical roles in cancer progression, thereby being regarded as an attractive …