[引用][C] Unexplored potential: Biologically active compounds produced by microorganisms from hard-to-reach environments and their applications

Z Cyske, W Jaroszewicz, M Żabińska… - Acta Biochimica …, 2021 - ojs.ptbioch.edu.pl
Rapid development of antibiotic resistance of bacteria and fungi, as well as cancer drug
resistance, has become a global medical problem. Therefore, alternative methods of …

[HTML][HTML] Bioactive molecules from extreme environments

D Giordano - Marine drugs, 2020 - mdpi.com
Marine organisms inhabiting extreme habitats are a promising reservoir of bioactive
compounds for drug discovery. Extreme environments, ie, polar and hot regions, deep sea …

Cryosphere: a frozen home of microbes and a potential source for drug discovery

S Zada, M Khan, Z Su, W Sajjad, M Rafiq - Archives of Microbiology, 2024 - Springer
The world is concerned about the emergence of pathogens and the occurrence and spread
of antibiotic resistance among pathogens. Drug development requires time to combat these …

Extremophiles: sustainable resource of natural compounds-extremolytes

R Kumar, DD Patel, DD Bansal, S Mishra… - … : sources of renewable …, 2010 - Springer
Microorganisms that thrive in extreme adverse environmental conditions are extremophiles.
Examples of these conditions are temperature (> 45° C;< 10° C), pressure (> 500 …

Extreme environments: microbiology leading to specialized metabolites

AM Sayed, MHA Hassan, HA Alhadrami… - Journal of applied …, 2020 - academic.oup.com
The prevalence of multidrug‐resistant microbial pathogens due to the continued misuse and
overuse of antibiotics in agriculture and medicine is raising the prospect of a return to the …

Antimicrobial compounds from natural sources

MA Hayashi, FC Bizerra, PI Da Silva Jr - Frontiers in microbiology, 2013 - frontiersin.org
Infectious diseases are one of the main causes of morbidity and mortality worldwide.
Nowadays many infections are often caused by multi-resistant microorganisms resulting in …

[HTML][HTML] Bioactive molecules from extreme environments II

D Giordano - Marine Drugs, 2021 - mdpi.com
Marine organisms are known to produce a wide variety of natural products that are unique in
terms of diversity, structural, and functional properties [1]. Marine organisms living in extreme …

Extremophiles: radiation resistance microbial reserves and therapeutic implications

OV Singh, P Gabani - Journal of applied microbiology, 2011 - academic.oup.com
Micro‐organisms with the ability to survive in extreme environmental conditions are known
as 'extremophiles'. Currently, extremophiles have caused a sensation in the biotechnology …

Secondary metabolites from bacteria and viruses

KD Pandey, AK Patel, M Singh, A Kumari - Natural bioactive compounds, 2021 - Elsevier
The majority of the bioactive compounds synthesized by bacteria as secondary metabolites
are low molecular mass products, not essential for the growth of producing organisms, but …

Molecules derived from the extremes of life: A decade later

ZE Wilson, MA Brimble - Natural Product Reports, 2021 - pubs.rsc.org
Covering: Early 2008 until the end of 2019 Microorganisms which survive (extreme-tolerant)
or even prefer (extremophilic) living at the limits of pH, temperature, salinity and pressure …