Effects of Lipid-Modifying and Other Drugs on Lipoprotein (a) Levels—Potent Clinical Implications

AD Koutsogianni, G Liamis, E Liberopoulos… - Pharmaceuticals, 2023 - mdpi.com
The past few years have shown an ongoing interest in lipoprotein (a)(Lp (a)), a lipid
molecule that has been proven to have atherogenic, thrombogenic, and inflammatory …

Lipoprotein (a): Cardiovascular risk and emerging therapies

M Fujino, SJ Nicholls - Expert Review of Cardiovascular Therapy, 2023 - Taylor & Francis
Introduction There is abundant evidence that elevated lipoprotein (a)[LP (a)] associates with
cardiovascular risk. Most lipid modifying therapies don't reduce Lp (a), but new technologies …

Lipoprotein (a): a risk factor for atherosclerosis and an emerging therapeutic target

SA Di Fusco, M Arca, P Scicchitano, A Alonzo… - Heart, 2023 - heart.bmj.com
Lipoprotein (a)(Lp (a)) is a complex circulating lipoprotein, and increasing evidence has
demonstrated its role as a risk factor for atherosclerotic cardiovascular disease (ASCVD) …

Latest developments in the treatment of lipoprotein (a)

S Bos, R Yayha, JER van Lennep - Current opinion in lipidology, 2014 - journals.lww.com
Latest developments in the treatment of lipoprotein (a) : Current Opinion in Lipidology Latest
developments in the treatment of lipoprotein (a) : Current Opinion in Lipidology Log in or …

Lipoprotein (a) as a biomarker for cardiovascular diseases and potential new therapies to mitigate risk

D Mukherjee, SE Nissen - Current Vascular Pharmacology, 2024 - ingentaconnect.com
Background: Lipoprotein (a)[Lp (a)] is a molecule that induces inflammation of the blood
vessels, atherogenesis, valvular calcification, and thrombosis. Methods: We review the …

Role of lipoprotein (a) in atherosclerotic cardiovascular disease: A review of current and emerging therapies

IS Alhomoud, A Talasaz, A Mehta… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Lipoprotein (a), or Lp (a), is structurally like low‐density lipoprotein (LDL) but differs
in that it contains glycoprotein apolipoprotein (a)[apo (a)]. Due to its prothrombotic and …

Lipoprotein (a) and atherosclerotic cardiovascular disease, the impact of available lipid-lowering medications on Lipoprotein (a): an update on new therapies

T Tsushima, Y Tsushima, C Sullivan, B Hatipoglu - Endocrine Practice, 2023 - Elsevier
Objective To review evidence of existing and new pharmacological therapies for lowering
lipoprotein (a)(Lp [a]) concentrations and their impact on clinically relevant outcomes …

Emerging therapeutic agents to lower lipoprotein (a) levels

B Kolski, S Tsimikas - Current opinion in lipidology, 2012 - journals.lww.com
Lp (a) remains the last major lipoprotein disorder without any specific therapy. With the
strong and accumulating data on its role as a causal risk factor for CVD, a rationale exists to …

Hyperlipidemia and cardiovascular disease: new insights on lipoprotein (a)

R Burkhardt - Current opinion in lipidology, 2019 - journals.lww.com
Elevated plasma level of LDL-cholesterol (LDL-C) is a modifiable major risk factor for
atherosclerotic cardiovascular disease. Several LDL-C-lowering agents successfully reduce …

[HTML][HTML] Lipoprotein (a): Role in atherosclerosis and new treatment options

DT Naglic, M Manojlovic, S Pejakovic… - Biomolecules and …, 2023 - ncbi.nlm.nih.gov
Atherosclerosis is a chronic process characterized by inflammation and the progressive
accumulation of inflammatory cells and lipids in the blood vessel wall, resulting in narrowing …