Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein with dual roles in redox
signaling and programmed cell death. Deficiency in AIF is known to result in defective …

Apoptosis-inducing factor (AIF) is a mitochondrial intermembrane space flavoprotein with
diverse functions in cellular physiology. In this regard, a large number of studies have …

Abstract Objectives Apoptosis-Inducing Factor (AIF) is a protein involved in mitochondrial
electron transport chain assembly/stability and programmed cell death. The relevant role of …

Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell
death programmes and participates in the assembly of the respiratory chain. Importantly, AIF …

Background Apoptosis is a hallmark of β-cell death in both type 1 and type 2 diabetes
mellitus. Understanding how apoptosis contributes to β-cell turnover may lead to strategies …

Apoptosis‐inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction,
translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show …

The mitochondrial flavoprotein apoptosis-inducing factor (AIF) is the main mediator of
caspase-independent apoptosis-like programmed cell death. Upon pathological …

Apoptosis-inducing factor (AIF) is a flavin adenine dinucleotide-containing, NADH-
dependent oxidoreductase residing in the mitochondrial intermembrane space whose …

Apoptosis-inducing factor (AIF) has important supportive as well as potentially lethal roles in
neurons. Under normal physiological conditions, AIF is a vital redox-active mitochondrial …

The X-linked AIFM1 gene encodes mitochondrial apoptosis-inducing factor (AIF), an FAD-
containing and NADH-specific oxidoreductase critically important for energy metabolism and …