Cancer therapy resistance (CTR) is the development of cancer resistance to multiple
therapeutic strategies, which severely affects clinical response and leads to cancer …

Several strategies, including chemotherapy and radiotherapy, have improved therapeutic
outcomes among cancer patients in clinical practice. However, due to their heterogeneity …

Marvelous advancements have been made in cancer therapies to improve clinical outcomes
over the years. However, therapeutic resistance has always been a major difficulty in cancer …

Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of
therapy resistance is a hot topic in epigenetics. As one of the most common RNA …

Drug resistance is perhaps the greatest obstacle in improving outcomes for cancer patients,
leading to recurrence, progression and metastasis of various cancers. Exploring the …

Despite the development of targeted therapy, drug resistance remains a primary hindrance
to curative treatment of various cancers. Among several novel approaches to overcome drug …

N6-methyladenosine (m6A) RNA methylation has been considered the most prevalent,
abundant, and conserved internal transcriptional modification throughout the eukaryotic …

Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant
cancers exhibit complex molecular mechanisms to hit back therapy under pharmacological …

N 6-Methyladenosine (m 6 A) RNA modification has emerged in recent years as a new layer
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …

Emergence of drug resistance to chemotherapeutic agents is the principal obstacle towards
curative cancer treatment in human cancer patients. It is in an urgent to explore the …