Nucleation, mapping and control of cavitation for drug delivery

E Stride, C Coussios - Nature Reviews Physics, 2019 - nature.com
Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Biomedical applications for gas-stabilizing solid cavitation agents

RG Thomas, US Jonnalagadda, JJ Kwan - Langmuir, 2019 - ACS Publications
For over a decade, advancements in ultrasound-enhanced drug delivery strategies have
demonstrated remarkable success in providing targeted drug delivery for a broad range of …

Ultrasound, cavitation bubbles and their interaction with cells

J Wu, WL Nyborg - Advanced drug delivery reviews, 2008 - Elsevier
This article reviews the basic physics of ultrasound generation, acoustic field, and both
inertial and non-inertial acoustic cavitation in the context of localized gene and drug delivery …

Cavitation bioeffects

E Kimmel - Critical Reviews™ in Biomedical Engineering, 2006 - dl.begellhouse.com
Acoustic cavitation takes place when tiny gas bubbles oscillate, grow, and collapse in liquid
under the influence of ultrasonic field. This study reviews cavitation bioeffects that are found …

Acoustic trapping of microbubbles in complex environments and controlled payload release

D Baresch, V Garbin - … of the National Academy of Sciences, 2020 - National Acad Sciences
Contactless manipulation of microparticles using acoustic waves holds promise for
applications ranging from cell sorting to three-dimensional (3D) printing and tissue …

Mechanistic understanding the bioeffects of ultrasound-driven microbubbles to enhance macromolecule delivery

P Qin, T Han, CH Alfred, L Xu - Journal of controlled release, 2018 - Elsevier
Ultrasound-driven microbubbles can trigger reversible membrane perforation
(sonoporation), open interendothelial junctions and stimulate endocytosis, thereby providing …

[HTML][HTML] Barrier-breaking effects of ultrasonic cavitation for drug delivery and biomarker release

Y Hu, J Wei, Y Shen, S Chen, X Chen - Ultrasonics Sonochemistry, 2023 - Elsevier
Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …

[HTML][HTML] Cavitation technology–a greener processing technique for the generation of pharmaceutical nanoemulsions

M Sivakumar, SY Tang, KW Tan - Ultrasonics sonochemistry, 2014 - Elsevier
Novel nanoemulsion-based drug delivery systems (DDS) have been proposed as
alternative and effective approach for the delivery of various types of poorly water-soluble …

Cavitation and contrast: the use of bubbles in ultrasound imaging and therapy

EP Stride, CC Coussios - … , Part H: Journal of Engineering in …, 2010 - journals.sagepub.com
Microbubbles and cavitation are playing an increasingly significant role in both diagnostic
and therapeutic applications of ultrasound. Microbubble ultrasound contrast agents have …