Programmed death ligand 1 (PD-L1) serves as a pivotal immune checkpoint in both the
innate and adaptive immune systems. PD-L1 is expressed in macrophages in response to …

Abstract PD-L1 (programmed death-ligand 1) serves as a pivotal immune checkpoint in both
the innate and adaptive immune systems. PD-L1 is expressed in macrophages in response …

Programmed cell death 1 ligand 1 (PD-L1) is an important immunosuppressive molecule,
which inhibits the function of T cells and other immune cells by binding to the receptor …

Abstract Programmed death-ligand 1 (PD-L1), an immune checkpoint ligand, is recognized
as a potential target for cancer immunotherapy as well as for the induction of transplantation …

Abstract PD-L1 (programmed death-ligand 1) is the ligand of PD-1 (programmed cell death
protein 1) and regulates inhibitory immune responses. It is well known that PD-L1 …

Programmed cell death-1 (PD-1) is a cell surface receptor that dampens adaptive immune
responses. PD-1 is activated by the engagement of its ligands PDL-1 or PDL-2. This results …

While programmed death-1 (PD-1), a co-inhibitory member of CD28 immunoglobulin
superfamily plays negative roles in effector functions of T cells and B cells, little is known …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population expanded
in cancer, infection and autoimmunity capable of suppressing T-cell functions. Checkpoint …

Chronic non-healing wounds fail to progress beyond the inflammatory phase, characterized
by a disorder of inflammation resolution. PD-1/PD-L1, a major co-inhibitory checkpoint …

Abstract Programmed death one (PD-1) is an inducible molecule belonging to the
immunoglobulin superfamily. It is expressed on activated T and B lymphocytes and plays …