Microglial cells are thought to colonize the human cerebrum between the 4th and 24th
gestational weeks. Rodent studies have demonstrated that these cells originate from yolk …

Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …

Microglia were recently shown to play unexpected roles in normal brain development and
adult physiology. This has begun to dramatically change our view of these resident …

Microglia are the resident macrophage population of the central nervous system (CNS).
Adequate microglial function is crucial for a healthy CNS. Microglia are not only the first …

Highlights•Microglia enter the brain as neurons begin to be generated.•Early microglia show
highly heterogeneous morphologies and distribution.•Embryonic functions of microglia are …

J. Neurochem.(2011) 119, 901–908. Abstract In all the species examined thus far, the
behavior of microglia during development appears to be highly stereotyped. This …

An explosion of findings driven by powerful new technologies has expanded our
understanding of microglia, the resident immune cells of the central nervous system (CNS) …

Microglia are macrophages that colonize the brain during development to establish a
resident population of professional phagocytes that protect against invading pathogens and …

Microglia are essential for the development and function of the adult brain. Microglia arise
from erythro-myeloid precursors in the yolk sac and populate the brain rudiment early during …

Microglia are brain macrophages that emerge from early erythro-myeloid precursors in the
embryonic yolk sac and migrate to the brain mesenchyme before the blood brain barrier is …