Supplementation with the Probiotic Strains Bifidobacterium longum and Lactiplantibacillus rhamnosus Alleviates Glucose Intolerance by Restoring the IL-22 …

WJ Kim, R Ryu, EH Doo, Y Choi, K Kim, BK Kim… - Probiotics and …, 2023 - Springer
Abstract Type 2 diabetes (T2D) is known as adult-onset diabetes, but recently, T2D has
increased in the number of younger people, becoming a major clinical burden in human …

The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice

J Hao, Y Zhang, T Wu, R Liu, W Sui, J Zhu, S Fang… - Food & Function, 2022 - pubs.rsc.org
Bifidobacterium longum subsp. longum BL21 (BL21) possesses hypoglycemic activity, but
its anti-diabetic mechanism has rarely been illustrated. In the present work, the effects of …

Effects of Bifidobacterium BL21 and Lacticaseibacillus LRa05 on gut microbiota in type 2 diabetes mellitus mice

Z Gai, W Liao, Y Huang, Y Dong, H Feng, M Han - AMB Express, 2023 - Springer
Gut dysbiosis causes damage to the intestinal barrier and is associated with type 2 diabetes
mellitus (T2DM). We tested the potential protective effects of probiotic BL21 and LRa05 on …

B. longum CKD1 enhances the efficacy of anti-diabetic medicines through upregulation of IL- 22 response in type 2 diabetic mice

WJ Kim, BJ Kil, C Lee, TY Kim, G Han, Y Choi… - Gut …, 2024 - Taylor & Francis
The gut microbiota plays a pivotal role in metabolic disorders, notably type 2 diabetes
mellitus (T2DM). In this study, we investigated the synergistic potential of combining the …

Bifidobacterium adolescentis Is Effective in Relieving Type 2 Diabetes and May Be Related to Its Dominant Core Genome and Gut Microbiota Modulation Capacity

X Qian, Q Si, G Lin, M Zhu, J Lu, H Zhang, G Wang… - Nutrients, 2022 - mdpi.com
The prevalence of diabetes mellitus is increasing globally. Probiotics have been shown to
be an effective intervention for diabetes. This study focused on the relieving effects and …

Oral administration of Bifidobacterium longum WHH2270 ameliorates type 2 diabetes in rats

K Gao, X Ren, C Chen, Q Fan, Y Li… - Journal of Food …, 2023 - Wiley Online Library
Accumulating evidence suggests that specific probiotic strains exert hypoglycemic effects on
type 2 diabetes mellitus (T2DM), and probiotic strains within Bifidobacterium exhibit potential …

Lactiplantibacillus plantarum Y15 alleviate type 2 diabetes in mice via modulating gut microbiota and regulating NF-κB and insulin signaling pathway

Y Liu, S Zheng, J Cui, T Guo, J Zhang - Brazilian Journal of Microbiology, 2022 - Springer
Probiotics have been used for the treatment of chronic metabolic diseases, including type 2
diabetes (T2D). However, the mechanisms of antidiabetic effects are not well understood …

The anti‐diabetic activity of Bifidobacterium lactis HY8101 in vitro and in vivo

SH Kim, CS Huh, ID Choi, JW Jeong… - Journal of Applied …, 2014 - academic.oup.com
Aims The aim of this study was to evaluate the effects of Bifidobacterium lactis HY8101 on
insulin resistance induced using tumour necrosis factor‐α (TNF‐α) in rat L6 skeletal muscle …

A Single Strain of Lactobacillus (CGMCC 21661) Exhibits Stable Glucose- and Lipid-Lowering Effects by Regulating Gut Microbiota

Y Wang, X Wang, X Xiao, S Yu, W Huang, B Rao… - Nutrients, 2023 - mdpi.com
Type 2 diabetes (T2D) is usually accompanied by obesity and nonalcoholic fatty-liver-
related insulin resistance. The link between T2D and dysbiosis has been receiving …

Multi-strain probiotic supplement attenuates streptozotocin-induced type-2 diabetes by reducing inflammation and β-cell death in rats

PS Hsieh, HH Ho, SP Tsao, SH Hsieh, WY Lin… - PLoS …, 2021 - journals.plos.org
Probiotics are health beneficial bacterial populations colonizing the human gut and skin.
Probiotics are believed to be involved in immune system regulation, gut microbiota …