[HTML][HTML] Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue
We have developed our original tissue engineering technology “cell sheet engineering”
utilizing temperature-responsive culture dishes. The cells are confluently grown on a …
utilizing temperature-responsive culture dishes. The cells are confluently grown on a …
Human induced pluripotent stem cell-derived fiber-shaped cardiac tissue on a chip
Y Morimoto, S Mori, F Sakai, S Takeuchi - Lab on a Chip, 2016 - pubs.rsc.org
We propose a method for the production of a fiber-shaped three-dimensional (3D) cellular
construct of human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) for the …
construct of human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) for the …
A novel method to align cells in a cardiac tissue‐like construct fabricated by cell sheet‐based tissue engineering
J Homma, S Shimizu, H Sekine… - Journal of Tissue …, 2020 - Wiley Online Library
Fabrication of cardiac tissue from human induced pluripotent stem cell‐derived
cardiomyocytes (hiPS‐CMs) has received great interest, but a major challenge facing …
cardiomyocytes (hiPS‐CMs) has received great interest, but a major challenge facing …
Simultaneous measurement of contractile force and field potential of dynamically beating human iPS cell-derived cardiac cell sheet-tissue with flexible electronics
Human induced pluripotent stem (iPS) cell-derived cardiomyocytes are used for in vitro
pharmacological and pathological studies worldwide. In particular, the functional …
pharmacological and pathological studies worldwide. In particular, the functional …
Human engineered heart tissue: analysis of contractile force
I Mannhardt, K Breckwoldt, D Letuffe-Brenière… - Stem cell reports, 2016 - cell.com
Analyzing contractile force, the most important and best understood function of
cardiomyocytes in vivo is not established in human induced pluripotent stem cell-derived …
cardiomyocytes in vivo is not established in human induced pluripotent stem cell-derived …
A new versatile platform for assessment of improved cardiac performance in human-engineered heart tissues
MC Ribeiro, JM Rivera-Arbeláez… - Journal of Personalized …, 2022 - mdpi.com
Cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) hold a great
potential as human in vitro models for studying heart disease and for drug safety screening …
potential as human in vitro models for studying heart disease and for drug safety screening …
3D printed micro-scale force gauge arrays to improve human cardiac tissue maturation and enable high throughput drug testing
Human induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) are regarded as
a promising cell source for establishing in-vitro personalized cardiac tissue models and …
a promising cell source for establishing in-vitro personalized cardiac tissue models and …
Functional arrays of human pluripotent stem cell-derived cardiac microtissues
To accelerate the cardiac drug discovery pipeline, we set out to develop a platform that
would be capable of quantifying tissue-level functions such as contractile force and be …
would be capable of quantifying tissue-level functions such as contractile force and be …
Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue
JL Ruan, NL Tulloch, MV Razumova, M Saiget… - Circulation, 2016 - Am Heart Assoc
Background: Tissue engineering enables the generation of functional human cardiac tissue
with cells derived in vitro in combination with biocompatible materials. Human-induced …
with cells derived in vitro in combination with biocompatible materials. Human-induced …
Differentiation of cardiomyocytes and generation of human engineered heart tissue
K Breckwoldt, D Letuffe-Brenière, I Mannhardt… - Nature protocols, 2017 - nature.com
Since the advent of the generation of human induced pluripotent stem cells (hiPSCs),
numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and …
numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and …
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