Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis

Z Cheng, L Li, X Mo, L Zhang… - International …, 2014 - spandidos-publications.com
The signal transducer and activator of transcription 3 (STAT3) signaling pathway has been
implicated in cell apoptosis and inflammatory processes. Ischemic preconditioning (IPC) and …

Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in …

P Li, L Su, X Li, W Di, X Zhang, C Zhang… - International Journal …, 2016 - Taylor & Francis
Remote ischemic postconditioning (RIPostC) is a promising therapeutic intervention, which
has been discovered to reduce ischemia/reperfusion (I/R) injury in heart, kidney, brain and …

Inhibition of the JAK2/STAT3 pathway and cell cycle re‐entry contribute to the protective effect of remote ischemic pre‐conditioning of rat hindlimbs on cerebral …

Y Zhao, M Ding, F Yan, J Yin, W Shi… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims Remote ischemic pre‐conditioning (RIPC) protects against ischemia/reperfusion (I/R)
injury. However, the mechanisms underlying this protection remain unclear. In the present …

Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the …

B Peng, Q Guo, Z He, Z Ye, Y Yuan, N Wang, J Zhou - Brain research, 2012 - Elsevier
Remote ischemic postconditioning (RIPoC) attenuates ischemia/reperfusion (I/R) injury in
the heart, lung and hind limb. RIPoC performed in the hind limb reduces brain injury …

Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal …

S Hu, H Dong, H Zhang, S Wang, L Hou, S Chen… - Brain research, 2012 - Elsevier
Purposes: To investigate whether activation of adenosine A1 receptor (A1R) through limb
remote ischemic preconditioning (RIPC) by a noninvasive tourniquet contribute …

The role of p38MAPK signal pathway in the neuroprotective mechanism of limb postconditioning against rat cerebral ischemia/reperfusion injury

H Li, S Zhou, L Wu, K Liu, Y Zhang, G Ma… - Journal of the neurological …, 2015 - Elsevier
It has been reported that remote ischemic postconditioning was able to protect from a
harmful ischemia occurring in brain. In the present study, we investigated the role of p38 …

Acute remote ischemic preconditioning alleviates free radical injury and inflammatory response in cerebral ischemia/reperfusion rats

XL Meng, DL Zhang, SH Sui - Experimental and …, 2019 - spandidos-publications.com
Remote ischemic preconditioning (IPreC) is an effective strategy to defend against cerebral
ischemia/reperfusion (IR) injury; however, its mechanisms remain to be elucidated. The aim …

Remote limb ischemic preconditioning protects rats against cerebral ischemia via HIF-1α/AMPK/HSP70 pathway

M Xia, Q Ding, Z Zhang, Q Feng - Cellular and molecular neurobiology, 2017 - Springer
Remote limb ischemic preconditioning (RIPC) is a clinically feasible strategy to protect
against ischemia/reperfusion injury, but the knowledge concerning the mechanism …

Role of the Janus kinase 2/signal transducers and activators of transcription 3 pathway in the protective effect of remote ischemia preconditioning against cerebral …

Y Zhao, Y Xue, Z Liu, S Ren, X Guan, M Li, X Zhao… - …, 2019 - journals.lww.com
Remote ischemia preconditioning (RIPC) is a convenient and effective method for alleviating
cerebral ischemia–reperfusion injury (CIRI). However, to date, the underlying mechanism …

A feasible strategy for focal cerebral ischemia-reperfusion injury: remote ischemic postconditioning

Q Liu, S Zhou, Y Wang, F Qi, Y Song… - Neural Regeneration …, 2014 - journals.lww.com
It is difficult to control the degree of ischemic postconditioning in the brain and other
ischemia-sensitive organs. Remote ischemic postconditioning could protect some ischemia …