Recent advances in our understanding of cardiovascular disease have revealed that
atherothrombotic events, such as myocardial infarction and ischemic stroke, are the end …

Inflammation is central to the pathogenesis and progression of atherosclerosis and
thrombosis, the underlying cause of major cardiovascular disease. Platelets, in addition to …

Platelets play a pivotal role in chronic inflammation leading to progression of atherosclerosis
and acute coronary events. Recent discoveries on novel mechanisms and platelet …

A clopidogrel loading dose administered during stenting attenuates inflammation marker
release. However, less is known of the anti-inflammatory effect of clopidogrel maintenance …

Objectives: This study was designed to evaluate the effects of long-term clopidogrel and
aspirin administration on platelet aggregation, activation, and inflammation. Background …

Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

Atherosclerosis is a pathological process caused by vascular remodeling. It symbolizes one
of the major causes for morbidity and mortality in the western world. The causes for these …

Platelets play an important role in the inflammatory response. In a nonrandomized
comparison, we examined the effect of clopidogrel pretreatment on platelet inflammatory …

Inflammation plays a key role in atherothrombosis: in the development of plaques, plaque
rupture and thrombus formation. Various biochemical substances have been shown to be …

Percutaneous coronary intervention (PCI) in patients presenting with acute coronary
syndrome (ACS) is associated with increased risk of thrombotic complications. ACS …