Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog

PR Houin, LA Veress, RC Rancourt… - Pediatric …, 2015 - Wiley Online Library
Background: Inhalation of sulfur mustard (SM) and SM analog, 2‐chloroethyl ethyl sulfide
(CEES), cause fibrinous cast formation that occludes the conducting airways, similar to …

Tissue plasminogen activator prevents mortality from sulfur mustard analog–induced airway obstruction

LA Veress, TB Hendry-Hofer, JE Loader… - American Journal of …, 2013 - atsjournals.org
Sulfur mustard (SM) inhalation causes the rare but life-threatening disorder of plastic
bronchitis, characterized by bronchial cast formation, resulting in severe airway obstruction …

Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation

LA Veress, HC O'Neill, TB Hendry-Hofer… - American journal of …, 2010 - atsjournals.org
Rationale: Sulfur mustard (SM) is a frequently used chemical warfare agent, even in modern
history. SM inhalation causes significant respiratory tract injury, with early complications due …

Sulfur mustard inhalation: mechanisms of injury, alteration of coagulation, and fibrinolytic therapy

CW White, RC Rancourt… - Annals of the New York …, 2016 - Wiley Online Library
Acute lung injury due to sulfur mustard (SM) inhalation causes the formation of airway fibrin
casts that obstruct airways at multiple levels, leading to acute respiratory failure and death …

Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation

RC Rancourt, A Ahmad, LA Veress… - American journal of …, 2014 - atsjournals.org
Acute lung injury in response to mustard gas (sulfur mustard [SM]) inhalation results in
formation of fibrin casts, which obstruct the airway. The objective of this study was to identify …

Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation

LA Veress, DR Anderson, TB Hendry-Hofer… - Toxicological …, 2015 - academic.oup.com
Rationale: Sulfur mustard (SM) is a chemical weapon stockpiled today in volatile regions of
the world. SM inhalation causes a life-threatening airway injury characterized by airway …

Bronchiolitis obliterans and pulmonary fibrosis after sulfur mustard inhalation in rats

MD McGraw, MM Dysart, TB Hendry-Hofer… - American Journal of …, 2018 - atsjournals.org
Inhalation of powerful chemical agents, such as sulfur mustard (SM), can have debilitating
pulmonary consequences, such as bronchiolitis obliterans (BO) and parenchymal fibrosis …

Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation

RC Rancourt, LA Veress, A Ahmad… - Toxicology and applied …, 2013 - Elsevier
Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability,
coagulation, and airway obstruction. The objective of this study was to determine whether …

Long-term respiratory effects of mustard vesicants

R Malaviya, JD Laskin, DL Laskin - Toxicology letters, 2020 - Elsevier
Sulfur mustard and related vesicants are cytotoxic alkylating agents that cause severe
damage to the respiratory tract. Injury is progressive leading, over time, to asthma …

From the cover: impairedproliferation and differentiation of the conducting airway epithelium associated with bronchiolitis obliterans after sulfur mustard inhalation …

MD McGraw, JS Rioux, RB Garlick… - Toxicological …, 2017 - academic.oup.com
Sulfur mustard (SM) is a chemical warfare agent that causes chronic airway remodeling.
This study's objective was to assess for changes to the bronchiolar epithelium after SM …