A peptide selectively recognizes Gram-negative bacteria and forms a bacterial extracellular trap (BET) through interfacial self-assembly
XL Sha, GT Lv, QH Chen, X Cui, L Wang… - Journal of Materials …, 2024 - pubs.rsc.org
An innate immune system intricately leverages unique mechanisms to inhibit colonization of
external invasive Bacteria, for example human defensin-6, through responsive …
external invasive Bacteria, for example human defensin-6, through responsive …
Combating bacterial infections with host defense peptides: Shifting focus from bacteria to host immunity
N Gao, J Wang, C Fang, P Bai, Y Sun, W Wu… - Drug Resistance …, 2023 - Elsevier
The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …
A biomimetic peptide recognizes and traps bacteria in vivo as human defensin-6
Y Fan, XD Li, PP He, XX Hu, K Zhang, JQ Fan… - Science …, 2020 - science.org
Using broad-spectrum antibiotics for microbial infection may cause flora disequilibrium, drug-
resistance, etc., seriously threatening human health. Here, we design a human defensin-6 …
resistance, etc., seriously threatening human health. Here, we design a human defensin-6 …
Surface-Induced Peptide Nanofibers for Selective Bacteria Trapping
The abuse of antibiotics has led to the emergence of various drug-resistant bacterial strains
that threaten human health. Other than a continuous screen for antibiotics, alternative …
that threaten human health. Other than a continuous screen for antibiotics, alternative …
Double-edged nanobiotic platform with protean functionality: Leveraging the synergistic antibacterial activity of a food-grade peptide to mitigate multidrug-resistant …
While persistent efforts are being made to develop a novel arsenal against bacterial
pathogens, the development of such materials remains a formidable challenge. One such …
pathogens, the development of such materials remains a formidable challenge. One such …
Biomaterial‐interrelated bacterial sweeper: simplified self‐assembled octapeptides with double‐layered Trp zipper induces membrane destabilization and bacterial …
Y Fang, Y Zhu, L Li, Z Lai, N Dong, A Shan - Small Methods, 2021 - Wiley Online Library
Abstract Treatment of microbial‐associated infections continues to be hampered by impaired
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …
[HTML][HTML] Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity
L Schnaider, S Brahmachari, NW Schmidt… - Nature …, 2017 - nature.com
Peptide-based supramolecular assemblies are a promising class of nanomaterials with
important biomedical applications, specifically in drug delivery and tissue regeneration …
important biomedical applications, specifically in drug delivery and tissue regeneration …
Bacteria‐Responsive Self‐Assembly of Antimicrobial Peptide Nanonets for Trap‐and‐Kill of Antibiotic‐Resistant Strains
Bacterial trapping using nanonets is a ubiquitous immune defense mechanism against
infectious microbes. These nanonets can entrap microbial cells, effectively arresting their …
infectious microbes. These nanonets can entrap microbial cells, effectively arresting their …
Mechanistic Investigation of a Self-Assembling Peptide against Escherichia coli
C Chen, G Li, X Cui, J Chen, Q Yu, C Zong, Y Zhao… - Langmuir, 2020 - ACS Publications
Because of their distinctive mode of action in targeting bacterial cell membranes,
antimicrobial peptides (AMPs) are increasingly regarded as a potential candidate for the …
antimicrobial peptides (AMPs) are increasingly regarded as a potential candidate for the …
Coassembled Multicomponent Protein Nanoparticles Elicit Enhanced Antibacterial Activity
The waning pipeline of the useful antibacterial arsenal has necessitated the urgent
development of more effective antibacterial strategies with distinct mechanisms to rival the …
development of more effective antibacterial strategies with distinct mechanisms to rival the …