Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

[HTML][HTML] Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment

JW Clancy, C D'Souza-Schorey - Annual Review of Pathology …, 2023 - annualreviews.org
Tumor cells release extracellular vesicles (EVs) that can function as mediators of
intercellular communication in the tumor microenvironment. EVs contain a host of bioactive …

The role of extracellular vesicles in cancer

R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer

C Sheehan, C D'Souza-Schorey - Journal of cell science, 2019 - journals.biologists.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound vesicles
released by cells that contain bioactive cargoes including proteins, lipids and nucleic acids …

[HTML][HTML] Extracellular vesicles in cancer: cell-to-cell mediators of metastasis

A Becker, BK Thakur, JM Weiss, HS Kim, H Peinado… - Cancer cell, 2016 - cell.com
Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant …

[HTML][HTML] Intercellular vesicular transfer by exosomes, microparticles and oncosomes-implications for cancer biology and treatments

R Jaiswal, LM Sedger - Frontiers in oncology, 2019 - frontiersin.org
Intercellular communication is a normal feature of most physiological interactions between
cells in healthy organisms. While cells communicate directly through intimate physiology …

[HTML][HTML] The role of extracellular vesicles in cancer: cargo, function, and therapeutic implications

J Jabalee, R Towle, C Garnis - Cells, 2018 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound structures
that play key roles in intercellular communication. EVs are potent regulators of …

[HTML][HTML] Extracellular vesicles: emerging targets for cancer therapy

P Vader, XO Breakefield, MJA Wood - Trends in molecular medicine, 2014 - cell.com
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
released by almost all cell types, including tumour cells. Through transfer of their molecular …

Extracellular vesicles and their roles in cancer progression

WH Chang, RA Cerione, MA Antonyak - Cancer cell signaling: Methods …, 2021 - Springer
Extracellular vesicles (EVs) produced by cancer cells function as a unique form of
intercellular communication that can promote cell growth and survival, help shape the tumor …