Amyloid plaques, the hallmark of Alzheimer's disease (AD), contain fibrillar β-amyloid (Aβ) 1-
40 and 1-42 peptides. Herpes simplex virus 1 (HSV-1) has been implicated as a risk factor …

Senile amyloid plaques are one of the main hallmarks of Alzheimer's disease (AD). They
correspond to insoluble deposits of amyloid-ß peptides (Aß) and are responsible for the …

Amyloid-ß (Aß) peptides generated by the amyloidogenic pathway of amyloid-ß protein
precursor processing contribute significantly to neurodegeneration characteristic of …

The amyloid-β (Aβ) peptide has long been considered to be the driving force behind
Alzheimer's disease (AD). However, clinical trials that have successfully reduced Aβ burden …

Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer's
disease (AD) pathology. We recently reported Aβ is an innate immune protein that protects …

The amyloid-β peptide (Aβ) is a key protein in Alzheimer's disease (AD) pathology. We
previously reported in vitro evidence suggesting that Aβ is an antimicrobial peptide. We …

Accumulation of β-Amyloid (βA) is a key pathogenetic factor in Alzheimer's disease;
however, the normal function of βA is unknown. Recent studies have shown that βA can …

Despite significant progress in the elucidation of the genetic basis of early-onset familial
Alzheimer's disease (AD), the etiology of sporadic cases remains elusive. Although certain …

Accumulation and aggregation of amyloid β peptide 1–42 (Aβ 42) in the brain has been
hypothesized as triggering a pathological cascade that causes Alzheimer disease (AD). To …

Amyloid-β (Aβ) peptides are the main components of the plaques found in the brains of
patients with Alzheimer's disease. However, Aβ peptides are also detectable in secretory …