The aim of this study is to investigate the effects of CYP11B2 gene polymorphisms with the
adrenocorticotropic hormone (ACTH) and angiotensin II (Ang II) in Chinese patients with …

Aldosterone synthase is a key enzyme in aldosterone production. Polymorphisms of the
aldosterone synthase gene, CYP11B2, have been suggested to be involved in the …

Background: It has been suggested that the− 344C/T polymorphism in the CYP11B2 gene is
involved in the development of hypertension. However, the results have been inconsistent …

Aldosterone synthase is a mitochondrial enzyme that catalyzes the conversion of 11-
deoxycorticosterone to the potent mineralocorticoid aldosterone. The gene encoding …

BACKGROUND: Aldosterone synthase (CYP11B2) is a key enzyme in the biosynthesis of
aldosterone. Recently, a C-344T polymorphism in the promoter region of the CYP11B2 gene …

Aldosterone is a hormone that affects both blood pressure and glucose homeostasis. We
studied the association of the aldosterone synthase gene (CYP11B2) polymorphism− 344T> …

Objective To explore the relationship between genetic polymorphisms of C-344T in the
promoter region and K173R in the exon 3 of aldosterone synthase gene (CYP11B2) and the …

Background The CYP17A1 gene encodes for cytochrome P450 enzyme CYP17A1, which is
involved with the steroidogenic pathway including mineralocorticoids. The CYP17A1 …

Objective. The cytochrome 11B2 aldosterone synthase gene (CYP11B2) that links to
aldosterone synthase enzyme synthesis changes and blood pressure regulation is of …

ABSTRACT Background and Objectives: Essential hypertension is a complex progressive
cardiovascular disorder. Renin–angiotensin aldosterone system (RAAS) plays a major role …