Type 1 diabetes affects millions of people globally and requires careful management to
avoid serious long-term complications, including heart and kidney disease, stroke, and loss …

Abstract Purpose of the Review Type 1 diabetes (T1D) is defined by an autoimmune
destruction of insulin producing β-cells located in the endocrine part of the pancreas, the …

Diabetes mellitus affects approximately 382 million individuals worldwide and is a leading
cause of morbidity and mortality. Over 40 and nearly 80 genetic loci influencing susceptibility …

The study of type 2 diabetes has been driven by advances in human genetics, epigenetics,
biomarkers, mechanistic studies, and large clinical trials, enabling new insights into disease …

Type 1 diabetes mellitus imposes a significant burden of complications and mortality,
despite important advances in treatment: subjects affected by this disease have also a worse …

Abstract The Precision Medicine Initiative defines precision medicine as 'an emerging
approach for disease treatment and prevention that takes into account individual variability …

Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells
located in the endocrine pancreas in areas known as islets of Langerhans. The current …

Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia resulting
from inadequate insulin signaling. Current management relies on biomarkers such as …

Type 1 diabetes mellitus (T1DM) is the most common chronic autoimmune disease in young
patients and is characterized by the loss of pancreatic β cells; as a result, the body becomes …

Type 1A (immune-mediated) and type 2 diabetes mellitus are two of the most common
severe chronic illnesses, affecting over 230 million people worldwide with an estimated …