A randomized double-blind trial of intranasal dexmedetomidine versus intranasal esketamine for procedural sedation and analgesia in young children

A Nikula, S Lundeberg, M Ryd Rinder… - Scandinavian Journal of …, 2024 - Springer
Background Procedural sedation and analgesia are commonly used in the Emergency
Departments. Despite this common need, there is still a lack of options for adequate and …

[HTML][HTML] Intranasal dexmedetomidine and rectal ketamine for young children undergoing burn wound procedures

A Frestadius, F Grehn, M Kildal, F Huss, F Fredén - Burns, 2022 - Elsevier
Background Safe and effective methods for sedation and analgesia in pediatric burn
patients are strongly warranted. This retrospective study of electronic health care records …

Analysis of 17 948 pediatric patients undergoing procedural sedation with a combination of intranasal dexmedetomidine and ketamine

F Yang, Y Liu, Q Yu, S Li, J Zhang, M Sun… - Pediatric …, 2019 - Wiley Online Library
Background Intranasal procedural sedation using dexmedetomidine is well described in the
literature. The combination of intranasal dexmedetomidine and ketamine is a novel …

The sedative effects of the intranasal administration of dexmedetomidine in children undergoing surgeries compared to other sedation methods: a systematic review …

HJ Kim, WJ Shin, S Park, HS Ahn, JH Oh - Journal of Clinical Anesthesia, 2017 - Elsevier
Study objective Administration of intranasal dexmedetomidine for sedation is comfortable
and effective in children who are afraid of needles, and it offers efficient sedation similar to …

Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and …

F Cossovel, A Trombetta, A Ramondo, G Riccio… - Italian Journal of …, 2022 - Springer
Background Non-painful diagnostic procedures require an inactive state for a prolonged
time, so that sedation is often needed in younger children to perform the procedures. Our …

Systematic review and meta‐analysis found that intranasal dexmedetomidine was a safe and effective sedative drug during paediatric procedural sedation

M Tervonen, T Pokka, M Kallio, O Peltoniemi - Acta paediatrica, 2020 - Wiley Online Library
Aim This systematic review and meta‐analysis evaluated the effectiveness of intranasal
dexmedetomidine as a sole sedative during paediatric procedural sedation outside the …

A comparison of intranasal dexmedetomidine, esketamine or a dexmedetomidine-esketamine combination for induction of anaesthesia in children: a randomized …

X Lu, L Tang, H Lan, C Li, H Lin - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: To compare the efficacy of dexmedetomidine, esketamine or combined intranasal
administration on the induction of inhalation anaesthesia in children. Methods: Ninety …

Intranasal dexmedetomidine as a sedative for pediatric procedural sedation

N Behrle, E Birisci, J Anderson… - The journal of …, 2017 - meridian.allenpress.com
OBJECTIVE This study seeks to evaluate the efficacy and safety of intranasal (IN)
dexmedetomidine as a sedative medication for non-invasive procedural sedation …

[PDF][PDF] Pre anaesthetic medication in children: a comparison of intranasal dexmedetomidine versus intranasal midazolam

DD Patel, M Lisha, MR Upadhyay - J Med Res, 2015 - medicinearticle.com
Background & objectives: Children are more anxious and fearful due to their limited
cognitive capabilities, lack of understanding of health care system and lack of self control. It …

Nurse-driven intranasal dexmedetomidine administration as sedation for non-invasive procedures in children: a single centre audit

E Goyens, K Allegaert, F De Buck, J Lauweryns… - European Journal of …, 2023 - Springer
The purpose of this study is to audit the efficacy and safety of intranasal dexmedetomidine
sedation for non-invasive procedural sedation in children provided by nurses of the …