The application of modern biochemical techniques has led to a rapid improvement in our
knowledge of the molecular biology of CMV. Several coding regions of the DNA genome …

The purpose of this article is to review immune responses to cytomegalovirus (CMV) which
may be initiated or guided by specific gene products of the virus. In light of the clinical …

Human cytomegalovirus is ubiquitous, yet causes little illness in immunocompetent
individuals. Disease is evident in immunodeficient groups such as neonates, transplant …

Human cytomegalovirus (HCMV), like all herpesviruses, persists in the host after primary
infection, with reactivation often occurring as a result of immunosuppression. The lack of a …

Although there are a number of excellent current reviews on one or another aspect of
cytomegalovirus, the last comprehensive treatment of this subject was that of Krech et …

Human cytomegalovirus (HCMV), a member of the herpesvirus group, is species specific
and can establish both persistent and latent infections. The virus appears to be able to infect …

We have determined the complete genome sequence of the Maastricht strain of rat
cytomegalovirus (RCMV). The RCMV genome has a length of 229,896 bp and is arranged …

Cytomegalovirus (CMV) is a ubiquitous agent that rarely causes disease in
immunocompetent humans but is an important cause of morbidity and mortality in the …

Defining causality between an agent-be it a virus, bacteria, or chemical—and a disease is
the principal aim of biomedical research. Achievement of this lofty goal is hampered when …

GENOME STRUCTURE The genome of HCMV is, as with other herpesviruses, linear
dsDNA of high complexity. The first attempts to determine the Mr of HCMV DNA led to the …