Background: Young patients are 6 times more likely than adults to have a primary anterior
cruciate ligament (ACL) graft failure. Biological factors (ie, tunnel osteolysis) may account for …

Objective To develop an imaging mass cytometry method for identifying complex cell
phenotypes, inter-cellular interactions, and population changes in the synovium and …

Objective To evaluate the degree of knee fat pad abnormalities after acute anterior cruciate
ligament (ACL) tear via magnetic resonance fat pad scoring and to assess cross-sectionally …

Objective Post-traumatic osteoarthritis (PTOA) is commonly studied using animal models.
Surgical ACL transection is an established model, but noninvasive models may mimic …

Objective and design The health of the infrapatellar fat pad (IFP) has been linked to pain,
joint inflammation, and the onset of post-traumatic osteoarthritis. Thus, early inflammation …

Anterior cruciate ligament (ACL) tears are a common knee injury with a known but poorly
understood association with secondary joint injuries and post‐traumatic osteoarthritis (OA) …

Subchondral bone is thought to play a significant role in the initiation and progression of the
post‐traumatic osteoarthritis. The goal of this study was to document changes in tibial and …

Background: Rupture of the anterior cruciate ligament (ACL) is a well-known risk factor for
the development of posttraumatic osteoarthritis (PTOA), but patients with the “same injury” …

Small animal models are essential for studying anterior cruciate ligament (ACL) injury, one
of the leading risk factors for post‐traumatic osteoarthritis (PTOA). Non‐surgical models of …

Joint instability and cartilage trauma have been previously studied and identified as key
mediators in the development of posttraumatic osteoarthritis (PTOA). The purpose of this …