Advancements in chimeric antigen receptor engineered T-cell (CAR-T) therapy have
revolutionized treatment for several cancer types over the past decade. Despite this success …

The clinical success stories of chimeric antigen receptor (CAR)-T cell therapy against B-cell
malignancies have contributed to immunotherapy being at the forefront of cancer therapy …

Natural killer (NK) cells, a unique component of the innate immune system, are inherent
killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells …

Cancer immunotherapies utilize the capabilities of the immune system to efficiently target
malignant cells. In recent years, chimeric antigen receptor (CAR) equipped T cells showed …

In recent years, cell-based immunotherapies have demonstrated promising results in the
treatment of cancer. Chimeric antigen receptors (CARs) arm effector cells with a weapon for …

Chimeric antigen receptor (CAR)-T cell therapies have achieved remarkable success.
However, application-related toxicities, such as cytokine release syndrome or neurotoxicity …

T cells engineered with chimeric antigen receptors (CARs) have revolutionized the field of
cell therapy and changed the paradigm of treatment for many patients with relapsed or …

Natural killer (NK) cells are a critical component of the innate immune system. Chimeric
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …

Adoptive cell treatment (ACT) utilizing chimeric antigen receptors (CAR) diverts the
specificity of safe cells against a target-specific antigen and portrays exceptional potential for …

Chimeric antigen receptors (CAR) are fusion proteins engineered from antigen recognition,
signaling, and costimulatory domains that can be used to reprogram T cells to specifically …