[PDF][PDF] Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue
Recent findings have demonstrated that mitochondria can be transferred between cells to
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …
control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a …
Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge
Brown adipose tissue (BAT) is a specialized thermogenic organ in mammals. The ability of
BAT mitochondria to generate heat in response to cold-challenge to maintain core body …
BAT mitochondria to generate heat in response to cold-challenge to maintain core body …
Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism
Beige adipocytes are an inducible form of mitochondria-enriched thermogenic adipocytes
that emerge in response to external stimuli, such as chronic cold exposure. We have …
that emerge in response to external stimuli, such as chronic cold exposure. We have …
A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice
EN Kuipers, NM Held… - American Journal …, 2019 - journals.physiology.org
Brown adipose tissue (BAT) catabolizes glucose and fatty acids to produce heat and thereby
contributes to energy expenditure. Long-term high-fat diet (HFD) feeding results in so-called …
contributes to energy expenditure. Long-term high-fat diet (HFD) feeding results in so-called …
[PDF][PDF] Intercellular mitochondria transfer to macrophages regulates white adipose tissue homeostasis and is impaired in obesity
Recent studies suggest that mitochondria can be transferred between cells to support the
survival of metabolically compromised cells. However, whether intercellular mitochondria …
survival of metabolically compromised cells. However, whether intercellular mitochondria …
Lipid droplets and mitochondria are anchored during brown adipocyte differentiation
Brown adipose tissue (BAT) acts as a site of non-shivering thermogenesis in mammals
including adult humans (Nedergaard and Cannon, 2010). Prolonged cold exposure can …
including adult humans (Nedergaard and Cannon, 2010). Prolonged cold exposure can …
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling
Combined fatty acid esterification and lipolysis, termed lipid cycling, is an ATP‐consuming
process that contributes to energy expenditure. Therefore, interventions that stimulate …
process that contributes to energy expenditure. Therefore, interventions that stimulate …
[HTML][HTML] Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing
E Gonzalez-Hurtado, J Lee, J Choi, MJ Wolfgang - Molecular metabolism, 2018 - Elsevier
Objective To determine the role of fatty acid oxidation on the cellular, molecular, and
physiologic response of brown adipose tissue to disparate paradigms of chronic …
physiologic response of brown adipose tissue to disparate paradigms of chronic …
Quantification of UCP1 function in human brown adipose tissue
C Porter - Adipocyte, 2017 - Taylor & Francis
Brown adipose tissue (BAT) mitochondria are distinct from their counterparts in other tissues
in that ATP production is not their primary physiologic role. BAT mitochondria are equipped …
in that ATP production is not their primary physiologic role. BAT mitochondria are equipped …
Mitochondrial regulation and white adipose tissue homeostasis
The important role of mitochondria in the regulation of white adipose tissue (WAT)
remodeling and energy balance is increasingly appreciated. The remarkable heterogeneity …
remodeling and energy balance is increasingly appreciated. The remarkable heterogeneity …