[HTML][HTML] Pancreatic ductal adenocarcinoma: Treatment hurdles, tumor microenvironment and immunotherapy
P Sarantis, E Koustas… - World journal of …, 2020 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, with an
average 5-year survival rate of less than 10%. Unfortunately, the majority of patients have …
average 5-year survival rate of less than 10%. Unfortunately, the majority of patients have …
Immunotherapy and pancreatic cancer: unique challenges and potential opportunities
Despite decades of research, pancreatic ductal adenocarcinoma (PDAC) continues to have
the worst 5-year survival of any malignancy. With 338,000 new cases diagnosed and over …
the worst 5-year survival of any malignancy. With 338,000 new cases diagnosed and over …
Advances in immunotherapeutics in pancreatic ductal adenocarcinoma
T Chouari, FS La Costa, N Merali, MD Jessel… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is the most common type of
pancreatic cancer, responsible for the majority of cases and ranking seventh as a leading …
pancreatic cancer, responsible for the majority of cases and ranking seventh as a leading …
Pancreatic cancer and immunotherapy: a clinical overview
FEF Timmer, B Geboers, S Nieuwenhuizen, M Dijkstra… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a
dismal prognosis. While immunotherapy has been deemed a breakthrough treatment for …
dismal prognosis. While immunotherapy has been deemed a breakthrough treatment for …
Current advances and outlooks in immunotherapy for pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is an incurable cancer resistant to traditional
treatments, although a limited number of early-stage patients can undergo radical resection …
treatments, although a limited number of early-stage patients can undergo radical resection …
Immunologic Strategies in Pancreatic Cancer: Making Cold Tumors Hot
NA Ullman, PR Burchard, RF Dunne… - Journal of Clinical …, 2022 - ascopubs.org
The rising incidence and persistent dismal 5-year overall survival of pancreatic ductal
adenocarcinoma (PDAC) highlight the need for new effective systemic therapies …
adenocarcinoma (PDAC) highlight the need for new effective systemic therapies …
Pancreatic ductal adenocarcinoma: a strong imbalance of good and bad immunological cops in the tumor microenvironment
ED Foucher, C Ghigo, S Chouaib, J Galon… - Frontiers in …, 2018 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers
with very few available treatments. For many decades, gemcitabine was the only treatment …
with very few available treatments. For many decades, gemcitabine was the only treatment …
Pancreatic ductal adenocarcinoma immune microenvironment and immunotherapy prospects
The tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) is non-
immunogenic, which consists of the stellate cells, fibroblasts, immune cells, extracellular …
immunogenic, which consists of the stellate cells, fibroblasts, immune cells, extracellular …
[HTML][HTML] Immunotherapy in pancreatic ductal adenocarcinoma: an emerging entity?
The genomic-plasticity of the immune system creates a broad immune repertoire engaged to
tackle cancer cells. Promising clinical activity has been observed with several immune …
tackle cancer cells. Promising clinical activity has been observed with several immune …
Broadening the impact of immunotherapy to pancreatic cancer: challenges and opportunities
VP Balachandran, GL Beatty, SK Dougan - Gastroenterology, 2019 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second deadliest
cancer in the United States by 2025, with 5-year survival at less than 10%. In other …
cancer in the United States by 2025, with 5-year survival at less than 10%. In other …