Adipose tissue immune cells in obesity, type 2 diabetes mellitus and cardiovascular diseases

A Cinkajzlová, M Mráz, M Haluzík - Journal of Endocrinology, 2022 - joe.bioscientifica.com
Immune cells are an inseparable component of adipose tissue intimately involved in most of
its functions. Physiologically, they regulate adipose tissue homeostasis, while in case of …

The role of adipose tissue immune cells in obesity and low-grade inflammation

M Mraz, M Haluzik - Journal of Endocrinology, 2014 - joe.bioscientifica.com
Adipose tissue (AT) lies at the crossroad of nutrition, metabolism, and immunity; AT
inflammation was proposed as a central mechanism connecting obesity with its metabolic …

The immune system of adipose tissue: obesity-associated inflammation

P Fischer-Posovszky, P Moeller - Der Pathologe, 2020 - europepmc.org
Adipose tissue is an important endocrine organ. Via its secretion products, it cross-talks with
other organs of the body and communicates the filling state of its triglyceride stores. Obesity …

Immune cells in adipose tissue: key players in metabolic disorders

K Lolmède, C Duffaut, A Zakaroff-Girard… - Diabetes & …, 2011 - Elsevier
Obesity, defined as the excess development of adipose tissue, is an important risk factor for
metabolic and cardiovascular diseases such as type 2 diabetes, hypertension and …

Innate immune cells in the adipose tissue

KJ Chung, M Nati, T Chavakis… - Reviews in Endocrine and …, 2018 - Springer
Immune cells are present in the adipose tissue (AT) and regulate its function. Under lean
conditions, immune cells predominantly of type 2 immunity, including eosinophils, M2-like …

Adipose tissue-resident immune cells in obesity and type 2 diabetes

J Lu, J Zhao, H Meng, X Zhang - Frontiers in immunology, 2019 - frontiersin.org
Inflammation is an important contributor to the pathogenesis of obesity-related type 2
diabetes (T2D). Adipose tissue-resident immune cells have been observed, and the …

The role of infiltrating immune cells in dysfunctional adipose tissue

TJ Guzik, DS Skiba, RM Touyz… - Cardiovascular …, 2017 - academic.oup.com
Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a
hallmark of non-communicable diseases. It is characterized by chronic low-grade …

Is the adipose tissue the key road to inflammation?

S Lucas, C Verwaerde… - Immunology and …, 2009 - journals.sagepub.com
It is now broadly accepted that white adipose tissue disorders, such as obesity, are
associated with a chronic low-grade inflammation predisposing to the development of …

Immunopathology of Adipose Tissue during Metabolic Syndrome.

M Ghazarian, H Luck, XS Revelo… - Turkish Journal of …, 2015 - search.ebscohost.com
Excess energy intake and a sedentary lifestyle have led to increasing incidence of obesity
which is a major risk factor for the development of insulin resistance. Research in the last …

Role of immune cells in obesity induced low grade inflammation and insulin resistance

A Asghar, N Sheikh - Cellular immunology, 2017 - Elsevier
The frequency of obesity is enormously growing worldwide. Obesity results when energy
intake exceeds, energy expenditure. Excess adiposity is a major risk factor in the progress of …