Probiotics treatment improves hippocampal dependent cognition in a rodent model of Parkinson's disease

C Xie, AA Prasad - Microorganisms, 2020 - mdpi.com
Parkinson's disease (PD) is a neurological disorder with motor dysfunction and a number of
psychiatric symptoms. Symptoms such as anxiety and cognitive deficits emerge prior to …

Neuroprotective and immunomodulatory effects of probiotics in a rat model of Parkinson's disease

I Parra, I Martínez, L Vásquez-Celaya… - Neurotoxicity …, 2023 - Springer
It is now well recognized that a bidirectional relationship between gut microbiota and the
brain, referred to as the gut-brain axis, plays a prominent role in maintaining homeostasis …

Probiotics alleviate the progressive deterioration of motor functions in a mouse model of Parkinson's disease

TH Hsieh, CW Kuo, KH Hsieh, MJ Shieh, CW Peng… - Brain sciences, 2020 - mdpi.com
Parkinson's disease (PD) is one of the common long-term degenerative disorders that
primarily affect motor systems. Gastrointestinal (GI) symptoms are common in individuals …

[HTML][HTML] Lactobacillus plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced mouse models of …

JF Liao, YF Cheng, ST You, WC Kuo, CW Huang… - Brain, behavior, and …, 2020 - Elsevier
Evidence suggests that the Parkinson's disease (PD) pathogenesis is strongly associated
with bidirectional pathways in the microbiota-gut-brain axis (MGBA), and psychobiotics may …

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

S Srivastav, S Neupane, S Bhurtel, N Katila… - The Journal of …, 2019 - Elsevier
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic …

Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease

DN Koutzoumis, M Vergara, J Pino, J Buddendorff… - Experimental …, 2020 - Elsevier
Parkinson's disease (PD) is a debilitating condition resulting in motor and non-motor
symptoms affecting approximately 10 million people worldwide. Currently, there are no …

Microbial treatment: the potential application for Parkinson's disease

X Fang - Neurological Sciences, 2019 - Springer
Alterations in the composition of the intestinal flora are associated with the pathophysiology
of Parkinson's disease (PD). More importantly, the possible cause-effect links between gut …

Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of …

T Ishii, H Furuoka, M Kaya, T Kuhara - Biomedicines, 2021 - mdpi.com
We previously reported that 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced
Parkinson's disease (PD) model mice (PD mice) facilitate hippocampal memory extinction …

Chronic treatment with the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis BB12 attenuates motor impairment, striatal microglial activation, and …

SG Cuevas-Carbonell, L Vásquez-Celaya… - Neuroscience, 2022 - Elsevier
Gut dysbiosis is considered a risk factor for Parkinson's disease (PD), and chronic treatment
with probiotics could prevent it. Here we report the assessment of a probiotic mixture …

Probiotics for Parkinson's disease: Current evidence and future directions

AH Tan, JW Hor, CW Chong, SY Lim - JGH Open, 2021 - Wiley Online Library
The gut–brain axis is a hot topic in Parkinson's disease (PD). It has been postulated that gut
pathogens and dysbiosis can contribute to peripheral inflammatory states or trigger …