Background: There is accumulating data suggesting an association between serum lipids,
apolipoproteins and disability in multiple sclerosis (MS). Objectives: To investigate the …

Background The breakdown of the blood-brain-barrier vascular endothelium is critical for
entry of immune cells into the MS brain. Vascular co-morbidities are associated with …

Background There is increasing evidence that serum lipids and apolipoproteins may be
associated with multiple sclerosis (MS) clinical course. Objective To investigate the …

Altered lipid metabolism is a feature of chronic inflammatory disorders. Increased plasma
lipids and lipoproteins have been associated with multiple sclerosis (MS) disease activity …

Background: Multiple sclerosis (MS) patients may be at an increased risk of comorbidities
due to the debilitating and chronic nature of the disease. An increased understanding of …

Objective To investigate the prospective associations between adiposity and lipid-related
variables and conversion to multiple sclerosis (MS), time to subsequent relapse and …

Multiple sclerosis (MS) is a chronic central nervous system disease that is associated with
progressive loss of myelin and subsequent axonal degeneration. Cholesterol is an essential …

Background: Previous studies evidenced a link between metabolic dysregulation,
inflammation, and neurodegeneration in multiple sclerosis (MS). Objectives: To explore …

Background and purpose Cholesterol is an important structural component of myelin and
essential for brain homeostasis. Our objective was to investigate whether longitudinal …

The purpose of this work was to determine whether changes in cholesterol profiles after
interferon-β (IFN-β) 1a treatment initiation following the first demyelinating event suggestive …