In most mammals, the oocyte is surrounded with compact multilayers of cumulus cells; these
form cumulusoocyte complexes (COCs). During oocyte maturation, the COCs dramatically …

Previous our studies have shown that CD44, the principal receptor for hyaluronan, is present
on cumulus cells during oocyte maturation. Although hyaluronan-CD44 interaction has been …

The process of cumulus expansion is a current topic of interest for in vitro production of
embryos. In the present study, we examined the components of cumulus expansion …

The transient synthesis and accumulation of hyaluronan (HA), an extracellular matrix
component of cumulus cells, brings about expansion of cumulus-oocyte complexes (COCs) …

Polyspermy is fairly common during porcine in vitro fertilisation (IVF), perhaps due to
incomplete in vitro oocyte maturation (IVM). Porcine cumulus cells (CCs) layered around the …

During oocyte maturation, the cumulus–oocyte complexes (COCs) expand dramatically. This
phenomenon, which is known as cumulus expansion, is the result of the synthesis and …

Hyaluronic acid-binding proteins (HABPs) are necessary for expansion of the cumulus-
oocyte complex (COC) during oocyte maturation. In this study, to obtain the detailed …

Hyaluronic acid (HA), an important component of the extracellular matrix, plays a crucial role
for cumulus cell expansion. Genes and proteins involved in HA synthesis and its receptor …

Abstract Changes in cell-to-cell contact and distribution of cytoskeletal components were
investigated during in vitro culture of cattle oocyte cumulus complexes (OCC). Freeze …

This review deals with molecular mechanisms controlling three important ovarian follicular
processes: 1) expansion of the cumulus, 2) synthesis of the hyaluronan (HA), and 3) …