In vitro dissolution and permeability testing aid the simulation of the in vivo behavior of
inhalation drug products. Although the regulatory bodies have specific guidelines for the …

The unique physiology of the lungs necessitates special considerations for developing a
robust and discriminate dissolution method for orally inhaled drug products (OIDPs). Despite …

The purpose of this article is to review the suitability of the analytical and statistical
techniques that have thus far been developed to assess the dissolution behavior of particles …

Dissolution testing is routinely used for quality control purposes to test batch‐to‐batch
consistency, stability and detect manufacturing deviations of pharmaceutical products. While …

In vitro dissolution testing is routinely used in the development of pharmaceutical products.
Whilst the dissolution testing methods are well established and standardized for oral dosage …

ABSTRACT The US Pharmacopeia (USP) contains standards for tests, procedures, and
acceptance criteria for inhalation dosage forms that are administered orally and intranasally …

Inhalation is the preferred route for the treatment of lung diseases. More recently, also
formulations for systemic treatment have been developed. For efficient development of …

The aim of this research project was to investigate a potential standardized test method to
characterize the dissolution properties of numerous formulation types available for …

The aim of this research was to investigate a potential standardized test method to
characterize the dissolution properties of formulations intended for pulmonary delivery. A …

Almost all current orally inhaled drug products (OIDPs) are for the treatment of respiratory
diseases, and many have been designed using molecular or formulation strategies to retain …