The impact of epitranscriptomics on antiviral innate immunity
B Mersinoglu, S Cristinelli, A Ciuffi - Viruses, 2022 - mdpi.com
Epitranscriptomics, ie, chemical modifications of RNA molecules, has proven to be a new
layer of modulation and regulation of protein expression, asking for the revisiting of some …
layer of modulation and regulation of protein expression, asking for the revisiting of some …
The emerging role of RNA modifications in the regulation of antiviral innate immunity
J Tong, W Zhang, Y Chen, Q Yuan, NN Qin… - Frontiers in …, 2022 - frontiersin.org
Posttranscriptional modifications have been implicated in regulation of nearly all biological
aspects of cellular RNAs, from stability, translation, splicing, nuclear export to localization …
aspects of cellular RNAs, from stability, translation, splicing, nuclear export to localization …
Post-transcriptional regulation of viral protein expression and function
S Zuñiga, JA Corcoran - Frontiers in Virology, 2023 - frontiersin.org
Post-transcriptional regulation includes both RNA and protein modifications, leading to the
modulation of protein expression levels or protein functions. These modifications may …
modulation of protein expression levels or protein functions. These modifications may …
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections
Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
viral infections. By modulating the modification landscape of viral and host RNAs, viruses …
Viral epitranscriptomics
Although it has been known for over 40 years that eukaryotic mRNAs bear internal base
modifications, it is only in the last 5 years that the importance of these modifications has …
modifications, it is only in the last 5 years that the importance of these modifications has …
The epitranscriptome and innate immunity
MA O'Connell, NM Mannion, LP Keegan - PLoS genetics, 2015 - journals.plos.org
Our knowledge of the variety and abundances of RNA base modifications is rapidly
increasing. Modified bases have critical roles in tRNAs, rRNAs, translation, splicing, RNA …
increasing. Modified bases have critical roles in tRNAs, rRNAs, translation, splicing, RNA …
[HTML][HTML] Proteomic analysis of antiviral innate immunity
JD Albarnaz, MP Weekes - Current Opinion in Virology, 2023 - Elsevier
Highlights•Antiviral innate immunity is regulated by changes in cellular proteins.•These
include changes in abundance, localisation, interaction and PTMs.•Viral immune evasion …
include changes in abundance, localisation, interaction and PTMs.•Viral immune evasion …
Regulation of antiviral innate immunity by chemical modification of viral RNA
N Li, TM Rana - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
More than 100 chemical modifications of RNA, termed the epitranscriptome, have been
described, most of which occur in prokaryotic and eukaryotic ribosomal, transfer, and …
described, most of which occur in prokaryotic and eukaryotic ribosomal, transfer, and …
Transcriptomics and quantitative proteomics in virology
A Berard, AL Kroeker, KM Coombs - Future Virology, 2012 - Taylor & Francis
Viral proteins and their roles in virus replication are typically well understood. However, their
interactions with host proteins are currently not as well defined, and a better understanding …
interactions with host proteins are currently not as well defined, and a better understanding …
Making the mark: the role of adenosine modifications in the life cycle of RNA viruses
SR Gonzales-van Horn, P Sarnow - Cell host & microbe, 2017 - cell.com
Viral epitranscriptomics is a newly emerging field that has identified unique roles for RNA
modifications in modulating life cycles of RNA viruses. Despite the observation of a handful …
modifications in modulating life cycles of RNA viruses. Despite the observation of a handful …