Pharmacologic therapy for pulmonary arterial hypertension in adults: CHEST guideline and expert panel report

DB Taichman, J Ornelas, L Chung, JR Klinger, S Lewis… - Chest, 2014 - Elsevier
OBJECTIVE Choices of pharmacologic therapies for pulmonary arterial hypertension (PAH)
are ideally guided by high-level evidence. The objective of this guideline is to provide …

Therapy for pulmonary arterial hypertension in adults: update of the CHEST guideline and expert panel report

JR Klinger, CG Elliott, DJ Levine, E Bossone, L Duvall… - Chest, 2019 - Elsevier
Background Pulmonary arterial hypertension (PAH) carries a poor prognosis if not promptly
diagnosed and appropriately treated. The development and approval of 14 medications over …

The pharmacological treatment of pulmonary arterial hypertension

LR Frumkin - Pharmacological reviews, 2012 - ASPET
Pulmonary arterial hypertension (PAH) is a life-threatening and progressive disease of
various origins characterized by pulmonary vascular remodeling that leads to increased …

Current treatment strategies for pulmonary arterial hypertension

SH Lee, LJ Rubin - Journal of internal medicine, 2005 - Wiley Online Library
Lee SH, Rubin LJ (University of California, San Diego, La Jolla, CA, USA). Current treatment
strategies for pulmonary arterial hypertension (Review). J Intern Med 2005; 258: 199–215 …

Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines

DB Badesch, SH Abman, G Simonneau, LJ Rubin… - Chest, 2007 - Elsevier
A consensus panel convened by the American College of Chest Physicians developed
guidelines for the treatment of pulmonary arterial hypertension (PAH) that were published in …

Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis

CJ Ryerson, S Nayar, JR Swiston, DD Sin - Respiratory research, 2010 - Springer
Background Previous meta-analyses of treatments for pulmonary arterial hypertension
(PAH) have not shown mortality benefit from any individual class of medication. Methods …

Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines

DB Badesch, SH Abman, GS Ahearn, RJ Barst… - Chest, 2004 - Elsevier
Pulmonary arterial hypertension (PAH) is often difficult to diagnose and challenging to treat.
Untreated, it is characterized by a progressive increase in pulmonary vascular resistance …

Evidence-based pharmacologic management of pulmonary arterial hypertension

N Benedict, A Seybert, MA Mathier - Clinical therapeutics, 2007 - Elsevier
Background: Pulmonary arterial hypertension (PAH) is a debilitating chronic disorder of the
pulmonary vasculature characterized by elevated mean pulmonary arterial pressure, right …

Updated evidence-based treatment algorithm in pulmonary arterial hypertension

RJ Barst, JSR Gibbs, HA Ghofrani, MM Hoeper… - Journal of the American …, 2009 - jacc.org
Uncontrolled and controlled clinical trials with different compounds and procedures are
reviewed to define the risk-benefit profiles for therapeutic options in pulmonary arterial …

Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension

N Galiè, W Seeger, R Naeije, G Simonneau… - Journal of the American …, 2004 - jacc.org
The numerous controlled clinical trials performed recently in pulmonary arterial hypertension
(PAH) can allow us to abandon a clinical-based treatment strategy and adopt an evidence …