Drospirenone (DRO) is a synthetic progestin derived from 17α-spironolactone with a
pharmacological mechanism of action similar to progesterone. Despite its wide use as …

Despite potential exposure of aquatic organisms to mixtures of steroid hormones, very little
is known on their joint activity in fish. Drospirenone (DRS) is a new synthetic progestin used …

Drospirenone (DRO) is one of the most widely used progestins in contraceptive treatments
and hormone replacement therapies. The pharmacokinetics and potential toxicological …

Synthetic progestins are emerging contaminants of the aquatic environment with endocrine
disrupting potential. The main aim of the present study was to investigate the effects of the …

Transcriptomics, high-throughput assays, and adverse outcome pathways (AOP) are
promising approaches applied to toxicity monitoring in the 21st century, but development of …

Marine mussels have been used as sentinel organisms to monitor exposure to a variety of
chemical contaminants, including endocrine disrupting chemicals, in the aquatic …

Drospirenone (DRS) is a synthetic progestin increasingly used in oral contraceptives with
similar effects to progesterone (P4). Wild fish are exposed to DRS and P4 through …

The presence of oral contraceptives (basically applying estrogens and/or progestogens)
poses a challenge to animals living in aquatic ecosystems and reflects a rapidly growing …

Progesterone (P4) and synthetic progestins enter the aquatic environment through
wastewater treatment plant effluents and agricultural run-off, posing potential risks to aquatic …

The presence of sex steroid hormones in aquatic ecosystems is of rapidly growing concern
worldwide since they can affect the different non-target species including cladocerans …