Detection of minimal residual disease

G Dölken - 2001 - Elsevier
A high percentage of patients with leukemia, lymphoma, and solid tumors achieve a
complete clinical remission after initial treatment, but the majority of these patients will finally …

Methods of minimal residual disease (MRD) detection in childhood haematological malignancies

J Jółkowska, K Derwich, M Dawidowska - Journal of applied genetics, 2007 - Springer
The appropriate management of haematological disorders must rely on a precise and long-
term monitoring of the patient's response to chemotherapy and radiotherapy. Clinical data …

Methods of minimal residual disease [MRD] detection in childhood haematological malignancies

J Jolkowska, K Derwich, M Dawidowska - Journal of Applied Genetics, 2007 - infona.pl
The appropriate management of haematological disorders must rely on a precise and long-
term monitoring of the patient's response to chemotherapy and radiotherapy. Clinical data …

The detection and significance of minimal residual disease in acute and chronic leukemia

NG Chung, V Buxhofer‐Ausch, JP Radich - Tissue Antigens, 2006 - Wiley Online Library
Minimal residual disease (MRD) can be detected in many patients with leukemia who have
achieved complete remission as defined by conventional pathology examination. The …

Detection and monitoring of minimal residual disease by quantitative real-time PCR

F Schüler, G Dölken - Clinica chimica acta, 2006 - Elsevier
BACKGROUND: The detection of malignant cells by quantitative real-time PCR has become
state of the art for diagnosis, monitoring response to treatment and detection of minimal …

Monitoring of minimal residual disease in leukemia, advantages and pitfalls

G Cazzaniga, G Gaipa, V Rossi, A Biondi - Annals of medicine, 2006 - Taylor & Francis
The term 'minimal residual disease'(MRD) defines the level of disease detectable in patients
in clinical remission during therapy, below the detection limit of conventional methods. Very …

Detection of minimal residual leukemia by polymerase chain reactions

CR Bartram - Molecular Diagnostics of Cancer, 1990 - Springer
Over the past two decades substantial progress has been made in the therapy of human
leukemias. This development can be illustrated by the success in the treatment of the most …

Optimizing molecular minimal residual disease analysis in adult acute lymphoblastic leukemia

I Della Starza, LA De Novi, L Elia, V Bellomarino… - Cancers, 2023 - mdpi.com
Simple Summary Minimal/measurable residual disease (MRD) monitoring is a powerful and
independent predictor of outcomes in both children and adult acute lymphoblastic leukemia …

Detection of minimal residual disease: relevance for diagnosis and treatment of human malignancies

C Hirsch-Ginsberg - Annual review of medicine, 1998 - annualreviews.org
Minimal residual disease (MRD) is the tumor burden that is present after a course of
treatment that has resulted in clinical remission. For hematopoietic malignancies, techniques …

Flow cytometry and allele-specific oligonucleotide PCR are equally effective in detection of minimal residual disease in ALL

M Malec, E Björklund, S Söderhäll, J Mazur… - Leukemia, 2001 - nature.com
The analysis of minimal residual disease (MRD) has assumed a growing role in the follow-
up of patients with acute lymphoblastic leukemia (ALL). We have applied multiparameter …