Our objective is to identify molecular factors which contribute to the increased risk of
smokers for oral squamous cell carcinoma (OSCC). In the present study, we investigated the …

Use of tobacco is responsible for∼ 30% of all cancer-related deaths in the United States,
including cancers of the upper aerodigestive tract. In the current study, 40 current and 40 …

In addition to being causally linked to the formation of multiple tumor types, tobacco use has
been associated with decreased efficacy of anticancer treatment and reduced survival time …

Cigarettes that burn tobacco produce a complex mixture of chemicals, including mutagens
and carcinogens. Cigarettes that primarily heat tobacco produce smoke with marked …

Smokeless tobacco (ST) usage is a growing public health problem worldwide. Exposure to
smokeless tobacco is carcinogenic to humans. The molecular mechanism (s) underlying ST …

United States, accounting for almost one third of all cancerrelated deaths and 90% of deaths
from lung cancer. Despite widespread knowledge of these risks, tobacco use prevalence …

Previous studies from different laboratories have demonstrated that cigarette smoke (CS)
harbours a strong oxidative stress potential, which broadly impacts exposed cells. Many of …

Background and Objective Smoking cigarettes increases the risk of oral tissue damage
leading to periodontal disease. Gingival fibroblasts, the predominant cell type inhabiting …

Smoking has been associated with diseases of the lung, pulmonary airways and oral cavity.
Cytologic, genomic and transcriptomic changes in oral mucosa correlate with oral pre …

Alcohol consumption and tobacco smoking are major causes of head and neck cancers, and
regional differences point to the importance of research into gene-environment interactions …