From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer
E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
Molecular heterogeneity in prostate cancer and the role of targeted therapy
Data collected from large-scale studies has shown that the incidence of prostate cancer
globally is on the rise, which could be attributed to an overall increase in lifespan. So, the …
globally is on the rise, which could be attributed to an overall increase in lifespan. So, the …
Human prostate cancer hallmarks map
D Datta, M Aftabuddin, DK Gupta, S Raha, P Sen - Scientific reports, 2016 - nature.com
Human prostate cancer is a complex heterogeneous disease that mainly affects elder male
population of the western world with a high rate of mortality. Acquisitions of diverse sets of …
population of the western world with a high rate of mortality. Acquisitions of diverse sets of …
Molecular pathways involved in prostate carcinogenesis: insights from public microarray datasets
Background Prostate cancer is currently the most frequently diagnosed malignancy in men
and the second leading cause of cancer-related deaths in industrialized countries …
and the second leading cause of cancer-related deaths in industrialized countries …
Precision medicine approach in prostate cancer
Prostate cancer is the most prevalent type of cancer and the second cause of death in men
worldwide. Various diagnostic and treatment procedures are available for this type of …
worldwide. Various diagnostic and treatment procedures are available for this type of …
[HTML][HTML] Bioinformatics and system biology approaches for identifying potential therapeutic targets for prostate cancer
Prostate cancer (PCa) is the primary cause of cancer-related deaths among men, and its
incidence increases with age. Despite the availability of treatments, the high costs and …
incidence increases with age. Despite the availability of treatments, the high costs and …
Complexities of prostate cancer
Prostate cancer has a long disease history and a wide variety and uncertainty in individual
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …
The genomic landscape of prostate cancer
L Spans, L Clinckemalie, C Helsen… - International journal of …, 2013 - mdpi.com
By the age of 80, approximately 80% of men will manifest some cancerous cells within their
prostate, indicating that prostate cancer constitutes a major health burden. While this …
prostate, indicating that prostate cancer constitutes a major health burden. While this …
[图书][B] An omics perspective on cancer research
WCS Cho - 2010 - Springer
Postgenome science is characterized by omics data related to genome, transcriptome,
epigenome, proteome, metabolome and interactome. In the omics era, it is a revolution in …
epigenome, proteome, metabolome and interactome. In the omics era, it is a revolution in …
The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches
AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …
support of clinical-pathological data such as the sum of the Gleason score and serum levels …