From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer

E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …

Molecular heterogeneity in prostate cancer and the role of targeted therapy

S Khan, P Baligar, C Tandon, J Nayyar, S Tandon - Life Sciences, 2023 - Elsevier
Data collected from large-scale studies has shown that the incidence of prostate cancer
globally is on the rise, which could be attributed to an overall increase in lifespan. So, the …

Human prostate cancer hallmarks map

D Datta, M Aftabuddin, DK Gupta, S Raha, P Sen - Scientific reports, 2016 - nature.com
Human prostate cancer is a complex heterogeneous disease that mainly affects elder male
population of the western world with a high rate of mortality. Acquisitions of diverse sets of …

Molecular pathways involved in prostate carcinogenesis: insights from public microarray datasets

SC Baetke, ME Adriaens, R Seigneuric, CT Evelo… - PloS one, 2012 - journals.plos.org
Background Prostate cancer is currently the most frequently diagnosed malignancy in men
and the second leading cause of cancer-related deaths in industrialized countries …

Precision medicine approach in prostate cancer

M Assadi, N Jokar, M Ghasemi… - Current …, 2020 - ingentaconnect.com
Prostate cancer is the most prevalent type of cancer and the second cause of death in men
worldwide. Various diagnostic and treatment procedures are available for this type of …

[HTML][HTML] Bioinformatics and system biology approaches for identifying potential therapeutic targets for prostate cancer

MAR Ashik, MA Hossain, SA Rahman, MS Akter… - Informatics in Medicine …, 2024 - Elsevier
Prostate cancer (PCa) is the primary cause of cancer-related deaths among men, and its
incidence increases with age. Despite the availability of treatments, the high costs and …

Complexities of prostate cancer

S Wasim, SY Lee, J Kim - International journal of molecular sciences, 2022 - mdpi.com
Prostate cancer has a long disease history and a wide variety and uncertainty in individual
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …

The genomic landscape of prostate cancer

L Spans, L Clinckemalie, C Helsen… - International journal of …, 2013 - mdpi.com
By the age of 80, approximately 80% of men will manifest some cancerous cells within their
prostate, indicating that prostate cancer constitutes a major health burden. While this …

[图书][B] An omics perspective on cancer research

WCS Cho - 2010 - Springer
Postgenome science is characterized by omics data related to genome, transcriptome,
epigenome, proteome, metabolome and interactome. In the omics era, it is a revolution in …

The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …