A markedly reduced interest or pleasure in activities previously considered pleasurable is a
main symptom in mood disorder and psychosis and is often present in other psychiatric …

Stress, especially chronic stress, is one of the most important factors responsible for
precipitation of affective disorders in humans. The animal models commonly used in the …

long standing definition of anhedonia as “the inability to experience pleasure” has been
challenged recently following progress in affective neuroscience. In particular, accumulating …

Deficits in reward and motivation are common symptoms characterizing several psychiatric
and neurological disorders. Such deficits may include anhedonia, defined as loss of …

Three behavioral paradigms are presented for the study of the mechanism of action of
antidepressant treatments and for the screening of new antidepressant drugs. The first …

Anhedonia, the lack of pleasure, has been shown to be a critical feature of a range of
psychiatric disorders. Yet, it is currently measured primarily through subjective self-reports …

Anhedonia is the inability to experience pleasure from normally pleasant stimuli. Although
anhedonia is a prominent feature of many psychiatric disorders, trait anhedonia is also …

Chronic sequential administration of a variety of mild stressors causes a decrease in
responsiveness to rewards in rats, which is reversed by chronic administration of …

Anhedonia, or loss of interest or pleasure in usual activities, is characteristic of depression,
some types of anxiety, as well as substance abuse and schizophrenia. Anhedonia is a …

Anhedonia refers to the reduced ability to experience pleasure, and has been studied in
different neuropsychiatrie disorders. Anhedonia is nevertheless considered as a core …