The frontal cortex has been implicated in a number of cognitive and motivational processes,
but understanding how individual neurons contribute to these processes is particularly …

Cognitive flexibility forms the core of the extraordinary ability of humans to adapt, but the
precise neural mechanisms underlying our ability to nimbly shift between task sets remain …

The frontal lobes play a key role in sequential organization of behavior. Little is known,
however, of the way frontal neurons code successive phases of a structured task plan. Using …

A long-lasting challenge in neuroscience has been to find a set of principles that could be
used to organize the brain into distinct areas with specific functions. Recent studies have …

The prefrontal cortex has a vital role in effective, organized behaviour. Both functional
neuroimaging in humans and electrophysiology in awake monkeys indicate that a …

Cognitive flexibility arises from our ability to shift behaviors depending on demand changes.
Behavioral shifting recruits both a preparatory process for an upcoming behavior and an …

The ability to shift between repetitive and goal-directed actions is a hallmark of cognitive
control. Previous studies have reported that adaptive shifts in behavior are accompanied by …

A common conceptualization of the organization of memory systems in brain is that different
types of memory are mediated by distinct neural systems. Strong support for this view comes …

Selecting behavioral outputs in a dynamic environment is the outcome of integrating multiple
information streams and weighing possible action outcomes with their value. Integration …

Neuronal representations change as associations are learned between sensory stimuli and
behavioral actions. However, it is poorly understood whether representations for learned …