[HTML][HTML] Serum KL-6 as a Candidate Predictor of Outcome in Patients with SARS-CoV-2 Pneumonia

S Kattner, S Sutharsan, MM Berger, A Limmer… - Journal of Clinical …, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-infection is associated
with an extremely variable disease course. When interstitial pneumonia (IP) occurs, it can …

[HTML][HTML] Serum KL-6 could represent a reliable indicator of unfavourable outcome in patients with COVID-19 pneumonia

R Scotto, B Pinchera, F Perna, L Atripaldi… - International Journal of …, 2021 - mdpi.com
KL-6 is a sialoglycoprotein antigen which proved elevated in the serum of patients with
different interstitial lung diseases, especially in those with a poorer outcome. Given that …

[HTML][HTML] Peak value of serum KL-6 may be useful for predicting poor prognosis of severe COVID-19 patients

S Maruyama, Y Nakamori, H Nakano… - European Journal of …, 2022 - Springer
Abstract Background Serum Krebs von den Lungen 6 (KL-6), which reflects alveolar
epithelial injury, was reported to be useful to predict the progression of pneumonitis induced …

Serum KL-6 level is a useful biomarker for evaluating the severity of coronavirus disease 2019

N Awano, M Inomata, N Kuse, M Tone, K Takada… - Respiratory …, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) is currently spreading
worldwide. This study examined whether serum Krebs von den Lungen-6 (KL-6) level is a …

[HTML][HTML] Increased KL-6 levels in moderate to severe COVID-19 infection

M Cambier, M Henket, AN Frix, S Gofflot, M Thys… - Plos one, 2022 - journals.plos.org
Background The global coronavirus disease 2019 (COVID-19) has presented significant
challenges and created concerns worldwide. Besides, patients who have experienced a …

Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling

TD Suryananda, R Yudhawati - Annals of medicine and surgery, 2021 - journals.lww.com
Background: The main target of SARS-CoV2 is the alveolar type II (AT2) cells of the lung.
SARS-CoV2 evades the innate immune system resulting in the release of proinflammatory …

[HTML][HTML] Usefulness of KL-6 for predicting clinical outcomes in hospitalized COVID-19 patients

M Park, M Hur, H Kim, CH Lee, JH Lee, M Nam - Medicina, 2022 - mdpi.com
Abstract Background: Krebs von den Lungen 6 (KL-6) is a novel biomarker for interstitial
lung disease, and it reflects acute lung injury. We explored the usefulness of KL-6 to predict …

Serum KL‐6 concentrations as a novel biomarker of severe COVID‐19

M d'Alessandro, P Cameli, RM Refini… - Journal of medical …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2–induced direct cytopathic effects against
type I and II pneumocytes mediate lung damage. Krebs von den Lungen‐6 (KL‐6) is mainly …

Clinical relevance of serum Krebs von den Lungen-6 levels in patients with coronavirus disease 2019

H Chen, R Qin, Z Huang, W Luo, P Zheng, H Huang… - Cytokine, 2021 - Elsevier
The clinical relevance of Krebs von den Lungen-6 (KL-6) levels in patients with coronavirus
disease 2019 (COVID-19) is unclear. This study aimed to evaluate the correlation between …

Prognostic value of serum Krebs von den Lungen-6 (KL-6) levels in COVID-19 pneumonia

A Letellier, C Rolland-Debord, D Luque-Paz… - … Medicine and Research, 2023 - Elsevier
Background and objectives Krebs von den Lungen-6 (KL-6), expressed by damaged type II
pneumocytes, is useful in the diagnosis and severity assessment of many diffuse interstitial …