We have compared the binding properties of c-JUN, JUN B, and JUN D in the absence or in
the presence of c-FOS, FOS B, and FRA-1 to different AP-1 and CRE-containing …

The proto-oncogene products Fos and Jun form a stable heterodimeric complex that
functions in transcriptional regulation by interacting with the DNA sequence known as the …

The protein products of the fos (Fos) and jun (Jun) proto-oncogenes have been shown to
associate with a DNA element known as the transcription factor activator protein-1 (AP-1) …

Comparison of the amino acid sequence of the three members of the mouse jun proto-
oncogene family, c-jun, jun B and jun D, reveals several homologous segments. The most C …

Publisher Summary This chapter discusses the structure of the cellular and retroviral jun
genes and their relationship to other transcriptional regulators. The interaction between the …

The DNA‐binding domains of the members of the Fos and Jun families of proteins consist of
a basic region followed by a dimerizing segment with heptad repeats of leucine. Fos‐Jun …

Jun and Fos oncoproteins form a complex that regulates transcription from promoters
containing AP-1 binding sites. The'leucine zipper'domain of both Fos and Jun is necessary …

The cFos proto-oncoprotein associates with cJun to form a heterodimer with increased DNA
binding and transcriptional activities. It has been suggested that dimerization of these …

The nuclear proto-oncogenes, c-fos and c-jun, are induced in response to a diverse array of
extracellular stimuli. Their protein products, Fos and Jun, form a heterodimeric complex that …

The protooncogenes c-fos and c-jun encode nuclear proteins (fos and jun, respectively) that
function cooperatively as a heterodimeric protein complex in the regulation of gene …