Metabolic methanol: molecular pathways and physiological roles

YL Dorokhov, AV Shindyapina… - Physiological …, 2015 - journals.physiology.org
Methanol has been historically considered an exogenous product that leads only to
pathological changes in the human body when consumed. However, in normal, healthy …

Formaldehyde in brain: an overlooked player in neurodegeneration?

K Tulpule, R Dringen - Journal of Neurochemistry, 2013 - Wiley Online Library
Formaldehyde is an environmental pollutant that is also generated in substantial amounts in
the human body during normal metabolism. This aldehyde is a well‐established neurotoxin …

Biological role of formaldehyde, and cycles related to methylation, demethylation, and formaldehyde production.

H Kalász - Mini reviews in medicinal chemistry, 2003 - europepmc.org
An overview is given on the analysis, formation, role and occurrence of formaldehyde in
living organisms. Various methods have been used for the determination of formaldehyde in …

[PDF][PDF] Toxicology and the biological role of methanol and ethanol: Current view.

M Pohanka - Biomedical Papers of the Medical Faculty of …, 2016 - biomed.papers.upol.cz
Background. Alcohol variants such as ethanol and methanol are simple organic compounds
widely used in foods, pharmaceuticals, chemical synthesis, etc. Both are becoming an …

Blood methanol concentrations during experimentally induced ethanol intoxication in alcoholics

E MAJCHROWICZ, JH MENDELSON - Journal of Pharmacology and …, 1971 - ASPET
Accumulation of methanol in blood was detected in alcoholic subjects during a 10-to 15-day
period of chronic alcohol intake. Blood methanol levels increased progressively from 0.2 to …

Ethanol metabolism

DW Crabb, WF Bosron, TK Li - Pharmacology & therapeutics, 1987 - Elsevier
The reduction of short chain aldehydes to alcohols is a common biological reaction which
allows the disposal of reducing equivalents during anaerobic metabolism by bacteria, fungi …

Defining a tolerable concentration of methanol in alcoholic drinks

AJ Paine, AD Dayan - Human & experimental toxicology, 2001 - journals.sagepub.com
Methanol, a potent toxicant in humans, occurs naturally at a low level in most alcoholic
beverages without causing harm. However, illicit drinks made from “industrial methylated …

Methanol poisoning: role of formate metabolism in the monkey

KE McMartin, G Martin-Amat, AB Makar… - Alcohol and aldehyde …, 1977 - Elsevier
Publisher Summary This chapter discusses the pathway responsible for formate oxidation in
the monkey and presents a comparison between the disposition of formate in the monkey …

Alzheimer's disease and methanol toxicity (part 2): lessons from four rhesus macaques (Macaca mulatta) chronically fed methanol

M Yang, J Miao, J Rizak, R Zhai… - Journal of …, 2014 - content.iospress.com
A recently established link between formaldehyde, a methanol metabolite, and Alzheimer's
disease (AD) pathology has provided a new impetus to investigate the chronic effects of …

[HTML][HTML] Ethanol metabolism: The good, the bad, and the ugly

DF Wilson, FM Matschinsky - Medical hypotheses, 2020 - Elsevier
Throughout the world, ethanol is both an important commercial commodity and a source of
major medical and social problems. Ethanol readily passes through biological membranes …