Drug‐induced liver injury (DILI) encompasses a spectrum of liver diseases from acute and
chronic hepatitis, cholestatic syndromes, and vascular lesions through to benign and …

Idiosyncratic drug induced liver injury (DILI) remains poorly understood. It is assumed that
the affected individuals possess a rare combination of genetic and non genetic factors that, if …

Drug-induced liver injury : Current Opinion in Gastroenterology Drug-induced liver injury :
Current Opinion in Gastroenterology Log in or Register Subscribe to journalSubscribe Get new …

Introduction: Idiosyncratic drug induced liver injury (DILI) is rare, with an incidence of
approximately 19 per 100,000 treated individuals. Areas covered: An update on the …

Clinical vignette A 21-year old woman was admitted to hospital with a two-week history of
painless jaundice, fatigue and anorexia having previously been fit and well. One month prior …

Drug-induced liver injury (DILI), also known as hepatotoxicity, refers to liver injury caused by
drugs or other chemical agents, and represents a special type of adverse drug reaction. It …

Acetaminophen overdose and idiosyncratic drug-induced liver injury (DILI) are the most
commonly identified causes of acute liver failure (ALF) in the United States. Suspected …

Drug-induced liver disease can result from dosage-dependent hepatotoxicity or from
adverse reactions to drugs used in therapeutic dosage. The latter idiosyncratic hepatotoxins …

Drug-induced liver injury (DILI) is an increasing health problem and a challenge for
physicians, regulatory bodies and the pharmaceutical industry, not only because of its …

Although severe idiosyncratic drug–induced liver injury (DILI) is a rare event, it has a large
impact on the fate of affected patients and the incriminated drug. Hepatic metabolism of …