Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

Defining polypharmacy in the elderly: a systematic review protocol

SS Mortazavi, M Shati, A Keshtkar, SK Malakouti… - BMJ open, 2016 - bmjopen.bmj.com
Introduction Ageing—along with its associated physiological and pathological changes—
places individuals at a higher risk of multimorbidity and treatment-related complications …

[HTML][HTML] Adverse outcomes of polypharmacy in older people: systematic review of reviews

LE Davies, G Spiers, A Kingston, A Todd… - Journal of the American …, 2020 - Elsevier
Objective Polypharmacy is widespread among older people, but the adverse outcomes
associated with it are unclear. We aim to synthesize current evidence on the adverse health …

Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis

M Delara, L Murray, B Jafari, A Bahji, Z Goodarzi… - BMC geriatrics, 2022 - Springer
Introduction Polypharmacy is commonly associated with adverse health outcomes. There
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …

Polypharmacy definitions for multimorbid older adults need stronger foundations to guide research, clinical practice and public health

C Sirois, NS Domingues, ML Laroche, A Zongo… - Pharmacy, 2019 - mdpi.com
There are numerous definitions of polypharmacy to describe the use of many medications
among older adults, but there is a need to clarify if they are purposive and meaningful. By …

[HTML][HTML] Polypharmacy—an upward trend with unpredictable effects

D Moßhammer, H Haumann, K Mörike… - Deutsches Ärzteblatt …, 2016 - ncbi.nlm.nih.gov
Background Guideline-oriented treatments can lead to polypharmacy, ie, the simultaneous
long-term use of multiple drugs. Polypharmacy mainly affects elderly patients. The goal of …