Sleep deprivation promotes endothelial inflammation and atherogenesis by reducing exosomal miR-182-5p

X Li, Y Cao, X Xu, C Wang, Q Ni, X Lv… - … , and vascular biology, 2023 - Am Heart Assoc
Background: Insufficient or disrupted sleep increases the risk of cardiovascular disease,
including atherosclerosis. However, we know little about the molecular mechanisms by …

Research progress on the role of exosomes in obstructive sleep apnea-hypopnea syndrome-related atherosclerosis

P Cai, Y Zheng, Y Zhou, M Li, YC Shi, H Lin… - Sleep Medicine …, 2022 - Elsevier
Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Atherosclerosis, a
multifactorial disease with complicated pathogenesis, is the main cause of CVD, underlying …

Effect on intermittent hypoxia on plasma exosomal micro RNA signature and endothelial function in healthy adults

A Khalyfa, C Zhang, AA Khalyfa, GE Foster… - Sleep, 2016 - academic.oup.com
Abstract Study Objective: Intermittent hypoxia (IH) is associated with increased risk of
cardiovascular disease. Exosomes are secreted by most cell types and released in …

Insufficient sleep is associated with a pro‐atherogenic circulating microRNA signature

JG Hijmans, M Levy, V Garcia… - Experimental …, 2019 - Wiley Online Library
New Findings What is the central question of the study Is habitual short sleep associated
with altered circulating levels of specific inflammation‐and vascular‐related microRNAs …

The therapeutic and diagnostic role of exosomes in cardiovascular diseases

P Zamani, N Fereydouni, AE Butler… - Trends in cardiovascular …, 2019 - Elsevier
Exosomes are nano-sized membranous vesicles that are secreted by cells. They have an
important role in transferring proteins, mRNA, miRNA and other bioactive molecules …

[HTML][HTML] Circulating exosomes from patients with peripheral artery disease influence vascular cell migration and contain distinct microRNA cargo

TA Sorrentino, P Duong, L Bouchareychas, M Chen… - JVS-vascular …, 2020 - Elsevier
Objective Peripheral artery disease (PAD) is a chronic condition characterized by
inflammation. Emerging literature suggests that circulating exosomes and their microRNA …

[HTML][HTML] Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis

Y Tang, LJ Yang, H Liu, YJ Song, QQ Yang, Y Liu… - Cell reports, 2023 - cell.com
Obesity, particularly increased visceral fat, positively correlates with various metabolic
challenges, including atherosclerosis, but the mechanism is not fully understood. The aim of …

[HTML][HTML] Adipose-derived mesenchymal stem cells-derived exosome-mediated microRNA-342-5p protects endothelial cells against atherosclerosis

X Xing, Z Li, X Yang, M Li, C Liu, Y Pang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Exosomes are reported to mediate several disease-related microRNAs (miRNAs) to affect
the progression of diseases, including atherosclerosis. Here, we aimed to screen the …

Circulating plasma extracellular microvesicle microRNA cargo and endothelial dysfunction in children with obstructive sleep apnea

A Khalyfa, L Kheirandish-Gozal, AA Khalyfa… - American journal of …, 2016 - atsjournals.org
Rationale: Obese children are at increased risk for developing obstructive sleep apnea
(OSA), and both of these conditions are associated with an increased risk for endothelial …

[HTML][HTML] The role of exosomes and exosomal microRNA in cardiovascular disease

D Zheng, M Huo, B Li, W Wang, H Piao… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …