The functional contribution of microglia to normal brain development, healthy brain function,
and neurological disorders is increasingly recognized. However, until recently, the nature of …

The continuous crosstalk between microglia and neurons is required for microglia
housekeeping functions and contributes to brain homeostasis. Through these exchanges …

Microglia are the primary immune cells of the central nervous system. However, recent data
indicate that microglia also contribute to diverse physiological and pathophysiological …

Investigations on the role of microglia in the brain have traditionally been focused on their
contributions to disease states. However, recent observations have now convincingly shown …

The traditional role of microglia has been in brain infection and disease, phagocytosing
debris and secreting factors to modify disease progression. Recent evidence extends their …

Microglia are tissue‐resident macrophages responsible for the surveillance, neuronal
support, and immune defense of the brain parenchyma. Recently, the role played by …

Brain function depends critically on the interactions among the underlying components that
comprise neural circuits. This includes coordinated activity in pre-synaptic and postsynaptic …

Recent findings challenge the concept that microglia solely function in disease states in the
central nervous system (CNS). Rather than simply reacting to CNS injury, infection, or …

Originally hypothesized to function solely as immunologic responders within the central
nervous system (CNS), emerging evidence has revealed that microglia have more complex …

Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …