Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes

C Yu, Y Ji, N Liu, Y Yang, M Wang, J Chen, W Zhu… - 2023 - researchsquare.com
The amygdala is a small but critical multi-nucleus structure for emotion, cognition, and
neuropsychiatric disorders. Although genetic associations with amygdala and subnucleus …

[HTML][HTML] The genetic architecture of human amygdala volumes and their overlap with common brain disorders

YN Ou, BS Wu, YJ Ge, Y Zhang, YC Jiang… - Translational …, 2023 - nature.com
The amygdala is a crucial interconnecting structure in the brain that performs several
regulatory functions, yet its genetic architectures and involvement in brain disorders remain …

[HTML][HTML] The genetic architecture of amygdala nuclei

MS Mufford, D van der Meer, T Kaufmann, O Frei… - Biological …, 2024 - Elsevier
Background Whereas genetic variants influencing total amygdala volume have been
identified, the genetic architecture of its distinct nuclei has yet to be explored. We aimed to …

Genetic correlations between subcortical brain volumes and psychiatric disorders

K Ohi, T Shimada, Y Kataoka, T Yasuyama… - The British Journal of …, 2020 - cambridge.org
Psychiatric disorders as well as subcortical brain volumes are highly heritable. Large-scale
genome-wide association studies (GWASs) for these traits have been performed. We …

Insights Into the Shared Genetic Architecture of Subcortical Brain Structures and Complex Human Traits

M Renteria… - Biological …, 2021 - biologicalpsychiatryjournal.com
Background Subcortical structures such as the hippocampus, ventral diencephalon,
brainstem, putamen and amygdala are involved in complex brain functions such as memory …

[PDF][PDF] Trans-ancestry genome-wide association meta-analyses of hippocampal and sub eld volumes

N Liu, L Zhang, T Tian, J Cheng, B Zhang, S Qiu… - researchsquare.com
The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and
its sub elds differ in architecture and function. Genome-wide association studies on …

Heritability of subcortical brain measures: a perspective for future genome-wide association studies

A Den Braber, MM Bohlken, RM Brouwer, D van't Ent… - NeuroImage, 2013 - Elsevier
Several large imaging-genetics consortia aim to identify genetic variants influencing
subcortical brain volumes. We investigated the extent to which genetic variation accounts for …

Investigating the genetic relationship of intracranial and subcortical brain volumes with depression and other psychiatric disorders

LM García-Marín, NS Ogonowski, LKM Han… - Imaging …, 2024 - direct.mit.edu
Depression is one of the most common mental health disorders worldwide, yet its
neurobiological mechanisms remain poorly understood. Structural brain differences in …

Trans-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes

C Yu, N Liu, L Zhang, T Tian, J Cheng, B Zhang, S Qiu… - 2022 - researchsquare.com
The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and
its subfields differ in cytoarchitecture, function and disease vulnerability. The genetic …

Impact of family history and depression on amygdala volume

K Saleh, A Carballedo, D Lisiecka, AJ Fagan… - Psychiatry Research …, 2012 - Elsevier
Family history of depression significantly impacts life-long depression risk. Family history
could impact the stress and emotion regulation system that involves the amygdala. This …