A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life

SB Jensen, AML Pedersen, A Vissink… - Supportive care in …, 2010 - Springer
Purpose This systematic review aimed to assess the literature for prevalence, severity, and
impact on quality of life of salivary gland hypofunction and xerostomia induced by cancer …

A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact

SB Jensen, AML Pedersen, A Vissink… - Supportive care in …, 2010 - Springer
Purpose This systematic review aimed to assess the literature for management strategies
and economic impact of salivary gland hypofunction and xerostomia induced by cancer …

Salivary gland hypofunction and/or xerostomia induced by nonsurgical cancer therapies: ISOO/MASCC/ASCO guideline

V Mercadante, SB Jensen, DK Smith… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide evidence-based recommendations for prevention and management
of salivary gland hypofunction and xerostomia induced by nonsurgical cancer therapies …

Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage

R Pinna, G Campus, E Cumbo, I Mura… - … and clinical risk …, 2015 - Taylor & Francis
Background The irradiation of head and neck cancer (HNC) often causes damage to the
salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce …

Salivary gland hypofunction and xerostomia in head and neck radiation patients

SB Jensen, A Vissink, KH Limesand… - JNCI …, 2019 - academic.oup.com
Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …

Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers

A Vissink, JB Mitchell, BJ Baum, KH Limesand… - International Journal of …, 2010 - Elsevier
The most significant long-term complication of radiotherapy in the head-and-neck region is
hyposalivation and its related complaints, particularily xerostomia. This review addresses …

The influence of xerostomia after radiotherapy on quality of life: results of a questionnaire in head and neck cancer

P Dirix, S Nuyts, V Vander Poorten, P Delaere… - Supportive Care in …, 2008 - Springer
Introduction Xerostomia is a common complication of radiotherapy for head and neck cancer
because irreparable damage is caused to the salivary glands if they are included in the …

Radiation‐induced xerostomia in patients with head and neck cancer: a literature review

P Dirix, S Nuyts… - … International Journal of …, 2006 - Wiley Online Library
A dry mouth or xerostomia is one of the most common complications during and after
radiotherapy for head and neck cancer, because irreparable damage is caused to the …

Interventions for the management of radiotherapy-induced xerostomia and hyposalivation: A systematic review and meta-analysis

V Mercadante, A Al Hamad, G Lodi, S Porter, S Fedele - Oral oncology, 2017 - Elsevier
Introduction Salivary gland hypofunction is a common and permanent adverse effect of
radiotherapy to the head and neck. Randomised trials of available treatment modalities have …

Xerostomia and hypofunction of the salivary glands in cancer therapy

S Jensen, A Pedersen, J Reibel, B Nauntofte - Supportive care in cancer, 2003 - Springer
This review presents data from the literature on oral adverse reactions from the perspectives
of subjective feelings of dry mouth (xerostomia) and objective measures of salivary gland …