[HTML][HTML] Design of a cryptococcus neoformans vaccine by subtractive proteomics combined with immunoinformatics

F Zhu, Z Zhou, S Ma, Y Xu, C Tan, H Yang… - International …, 2024 - Elsevier
The emergence of Cryptococcus neoformans has posed an undeniable burden to many
regions worldwide, with its strains mainly entering the lungs through the respiratory tract and …

Immunoinformatic-guided designing and evaluating protein and mRNA-based vaccines against Cryptococcus neoformans for immunocompromised patients

A Elalouf, A Yaniv-Rosenfeld - Journal of Genetic Engineering and …, 2023 - Elsevier
Background Cryptococcus neoformans is a fungal pathogen that can cause serious
meningoencephalitis in individuals with compromised immune systems due to HIV/AIDS …

Epitope‐Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii

RM Elhassan, NM Alsony, KM Othman… - Journal of …, 2021 - Wiley Online Library
Introduction. Cryptococcosis is a ubiquitous opportunistic fungal disease caused by
Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV …

Computational vaccinology approach: Designing an efficient multi-epitope peptide vaccine against Cryptococcus neoformans var. grubii's heat shock 70KDa protein

RM Elhassan, NM Alsony, KM Othman, DT Izz-Aldin… - BioRxiv, 2019 - biorxiv.org
Introduction Cryptococcosis is a ubiquitous opportunistic fungal disease caused by
Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV …

Integrating core subtractive proteomics and reverse vaccinology for multi-epitope vaccine design against Rickettsia prowazekii endemic typhus

A Khan, MH Khanzada, K Khan, K Jalal, R Uddin - Immunologic Research, 2024 - Springer
Rickettsia prowazekii is an intracellular, obligate, gram-negative coccobacillus responsible
for epidemic typhus. Usually, the infected body louse or its excrement when rubbed into the …

Design of an epitope-based peptide vaccine against Cryptococcus neoformans

I Khalil, I Omer, IZA Farh, HA Mohamed, HA Elsharif… - BioRxiv, 2018 - biorxiv.org
Introduction This study aimed to design an immunogenic epitope for Cryptococcus
neoformans the etiological agent of cryptococcosis using in silico simulations, for epitope …

[HTML][HTML] Integrated immunoinformatics and subtractive proteomics approach for multi-epitope vaccine designing to combat S. pneumoniae TIGR4

SS Ashgar, H Faidah, F Bantun, NA Jalal… - Frontiers in Molecular …, 2023 - frontiersin.org
Streptococcus pneumoniae is one of the major precarious pathogens accountable for over
1.2 million fatalities annually. The key drivers for pneumococcal vaccine development …

[HTML][HTML] Whole proteome-based therapeutic targets annotation and designing of multi-epitope-based vaccines against the gram-negative XDR-Alcaligenes faecalis …

M Alharbi, A Alshammari, AF Alasmari, S Alharbi… - Vaccines, 2022 - mdpi.com
This study involved therapeutic targets mining for the extremely drug-resistant bacterial
species called Alcaligenes faecalis, which is known to infect humans. The infections caused …

A comprehensive immunoinformatic analysis of chitin deacetylase's and MP88 for designing multi-epitope vaccines against Cryptococcus neoformans

MAS Khan, MI Miah, SR Rahman - Journal of Biomolecular …, 2023 - Taylor & Francis
Cryptococcus neoformans causes life-threatening pneumonia and meningitis and is
regarded as one of the leading killers of immunocompromised individuals. There is currently …

[HTML][HTML] Multi-epitope chimeric vaccine designing and novel drug targets prioritization against multi-drug resistant Staphylococcus pseudintermedius

S Jaan, M Shah, N Ullah, A Amjad, MS Javed… - Frontiers in …, 2022 - frontiersin.org
Biofilm synthesizing multi-drug resistant Staphylococcus pseudintermedius bacteria has
been recognized as the human infectious agent. It has been detected in the diseases of skin …