Cepharanthine: A review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

M Rogosnitzky, P Okediji, I Koman - Pharmacological Reports, 2020 - Springer
Cepharanthine (CEP) is a naturally occurring alkaloid derived from Stephania cepharantha
Hayata and demonstrated to have unique anti-inflammatory, antioxidative …

Pharmacological effects and clinical prospects of cepharanthine

D Liang, Q Li, L Du, G Dou - Molecules, 2022 - mdpi.com
Cepharanthine is an active ingredient separated and extracted from Stephania cepharantha
Hayata, a Menispermaceae plant. As a bisbenzylisoquinoline alkaloid, cepharanthine has …

Cepharanthine: A Promising Old Drug against SARS‐CoV‐2

H Fan, S He, P Han, B Hong, K Liu, M Li… - Advanced …, 2022 - Wiley Online Library
Recently, the inhibiting effects of a clinically approved drug Cepharanthine on severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) have attracted widespread attention and …

Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐2

A Hijikata, C Shionyu‐Mitsuyama, S Nakae… - FEBS Open …, 2022 - Wiley Online Library
Cepharanthine (CEP) is a natural biscoclaurine alkaloid of plant origin and was recently
demonstrated to have anti‐severe acute respiratory syndrome coronavirus 2 (anti‐SARS …

[PDF][PDF] Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment

H Ohashi, K Watashi, W Saso, K Shionoya, S Iwanami… - Iscience, 2021 - cell.com
Antiviral treatments targeting the coronavirus disease 2019 are urgently required. We
screened a panel of already approved drugs in a cell culture model of severe acute …

Cytokine storm in COVID‐19 and parthenolide: Preclinical evidence

M Bahrami, M Kamalinejad, SA Latifi… - Phytotherapy …, 2020 - Wiley Online Library
A group of patients with pneumonia caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) were reported from China in December 2019. Although …

High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents

P Kanjanasirirat, A Suksatu, S Manopwisedjaroen… - Scientific reports, 2020 - nature.com
Since December 2019, the emergence of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has caused severe pneumonia, a disease named COVID-19, that became …

Naturally available flavonoid aglycones as potential antiviral drug candidates against SARS-CoV-2

AA Al-Karmalawy, MM Farid, A Mostafa, AY Ragheb… - Molecules, 2021 - mdpi.com
Flavonoids are important secondary plant metabolites that have been studied for a long time
for their therapeutic potential in inflammatory diseases because of their cytokine-modulatory …

[HTML][HTML] Carvacrol, a plant metabolite targeting viral protease (Mpro) and ACE2 in host cells can be a possible candidate for COVID-19

H Javed, MFN Meeran, NK Jha, S Ojha - Frontiers in Plant Science, 2021 - frontiersin.org
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
started in December 2019, resulting in the coronavirus disease-19 (COVID-19) pandemic …

[HTML][HTML] Artemether, Artesunate, Arteannuin B, Echinatin, Licochalcone B and Andrographolide Effectively Inhibit SARS-CoV-2 and Related Viruses In Vitro

Y Hu, M Liu, H Qin, H Lin, X An, Z Shi… - Frontiers in cellular …, 2021 - frontiersin.org
Since the first reported case caused by the novel coronavirus SARS-CoV-2 infection in
Wuhan, COVID-19 has caused serious deaths and an ongoing global pandemic, and it is …